Evidence map›Paper›PMID 40720840›Full record

ArticleGigaScience2025

Reducing skin microbiome exposure impacts through swine farm biosecurity.

Ilya B Slizovskiy, Tara N Gaire, Peter M Ferm, Carissa A Odland, Scott A Dee, Joel Nerem, Jonathan E Bravo, Alejandro D Kimball, Christina Boucher, Noelle R Noyes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GigaScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ilya B SlizovskiyPurdue Applied Microbiome Sciences Program, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0002-0758-5510
Tara N GaireDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0003-1805-8051
Peter M FermDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0009-0008-8873-0185
Carissa A OdlandPipestone Veterinary Services, Pipestone, MN 56164, USA.ORCID 0000-0003-0787-4985
Scott A DeePipestone Applied Research, Pipestone, MN 56164, USA.ORCID 0000-0001-8691-3887
Joel NeremPipestone Applied Research, Pipestone, MN 56164, USA.
Jonathan E BravoDepartment of Computer and Information Science and Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-4481-8766
Alejandro D KimballRegenstrief Center for Healthcare Engineering, Purdue University, West Lafayette, IN 47904, USA.ORCID 0009-0002-4787-6176
Christina BoucherDepartment of Computer and Information Science and Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0001-9509-9725
Noelle R NoyesDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0001-6149-1008

Funding

Developing Computational Methods for Surveillance of Antimicrobial Resistant AgentsR01AI141810 · NIAID · UNIVERSITY OF FLORIDA · PI BOUCHER, CHRISTINA, PROSPERI, MATTIA · 2019 to 2023
$2.1M
National Institute of Allergy and Infectious Diseases 1R01AI141810-01NIAID NIH HHS R01 AI141810NIH HHSNIOSH CDC HHS 5U54OH010170-13ANIOSH CDC HHS U54 OH010170
6 · The paper itself

Abstract

backgroundLivestock work is unique due to worker exposure to animal-associated microbiomes within the workplace. Swine workers are a unique cohort within the US livestock labor force, as they have direct daily contact with pigs and undertake mandatory biosecurity interventions. However, investigating this occupational cohort is challenging, particularly within tightly regulated commercial swine operations. Thus, little is known about the impacts of animal exposure and biosecurity protocols on the swine worker microbiome. We obtained unique samples from US swine workers, using a longitudinal study design to investigate temporal microbiome dynamics.

resultsWe observed a significant increase in bacterial DNA load on worker skin during the workday, with concurrent changes in the composition and abundance of microbial taxa, resistance genes, and mobile genetic elements. However, mandatory showering at the end of the workday partially returned the skin's microbiome and resistome to their original state.

conclusionsThese novel results from a human cohort demonstrate that existing biosecurity practices can ameliorate work-associated microbiome impacts.

Indexed as

BiosecurityMicrobiotaOccupational ExposureSkinAdultAnimal HusbandryAnimalsBacteriaFarmsFemaleHumansLongitudinal StudiesMaleSkin MicrobiomeSwineantimicrobial resistancefarmworkersmetagenomicsmicrobiomemobile genetic elementspublic health

Identifiers

PMID40720840
PMCPMC12810053

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.