Evidence map›Paper›PMID 40720830›Full record

ArticleACS synthetic biology2025

CRISPR-Cas10-Assisted Structural Modification of Staphylococcal

Hana Šimečková, Pavol Bárdy, Lucie Kuntová, Eliška Macháčová, Tibor Botka, Ján Bíňovský, Josef Houser, Zdeněk Farka, Pavel Plevka, Roman Pantůček and 1 more

Abstract read
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hana ŠimečkováDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.
Pavol BárdyDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.
Lucie KuntováDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.
Eliška MacháčováDepartment of Biochemistry, Faculty of Science, Masaryk University, Brno 625 00, Czech Republic.
Tibor BotkaDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.
Ján BíňovskýCentral European Institute of Technology, Masaryk University, Brno 625 00, Czech Republic.ORCID 0000-0001-7647-5211
Josef HouserCentral European Institute of Technology, Masaryk University, Brno 625 00, Czech Republic.
Zdeněk FarkaDepartment of Biochemistry, Faculty of Science, Masaryk University, Brno 625 00, Czech Republic.ORCID 0000-0002-6842-7081
Pavel PlevkaCentral European Institute of Technology, Masaryk University, Brno 625 00, Czech Republic.
Roman PantůčekDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.ORCID 0000-0002-3950-675X
Ivana MašlaňováDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno 611 37, Czech Republic.ORCID 0000-0002-2597-2848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in genome editing techniques based on CRISPR-Cas have opened up new possibilities in bacteriophage engineering and, thus, enabled key developments in medicine, nanotechnology, and synthetic biology. Although staphylococcal phage genomes have already been edited, the modification of their structural proteins has not yet been reported. Here, the structure of

Indexed as

Biosensing TechniquesCRISPR-Cas SystemsStaphylococcus PhagesGene EditingStaphylococcusBacteriophageBiosensing TechniquesCRISPR-Cas10HerelleviridaePoly histidine TagStaphylococcus aureus

Identifiers

PMID40720830
PMCPMC12362608

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.