Evidence map›Paper›PMID 40720818›Full record

Observational studyJournal of medical Internet research2025

Capturing Real-World Habitual Sleep Patterns With a Novel User-Centric Algorithm to Preprocess Fitbit Data in the All of Us Research Program: Retrospective Observational Longitudinal Study.

Hiral Master, Jeffrey Annis, Jack H Ching, Karla Gleichauf, Lide Han, Peyton Coleman, Kelsie M Full, Neil Zheng, Douglas Ruderfer, John Hernandez and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiral Master *Vanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0003-0019-3087
Jeffrey Annis *Vanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0002-3097-4186
Jack H Ching *Google, Mountain View, CA, United States.ORCID https://orcid.org/0000-0003-0752-8628
Karla GleichaufGoogle, Mountain View, CA, United States.ORCID https://orcid.org/0009-0009-9572-4223
Lide HanVanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0002-9077-7766
Peyton ColemanVanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0001-5388-6886
Kelsie M FullVanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0002-6264-0228
Neil ZhengBrigham and Women's Hospital, Boston, MA, United States.ORCID https://orcid.org/0000-0001-8737-0773
Douglas RuderferVanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0002-2365-386X
John HernandezGoogle, Mountain View, CA, United States.ORCID https://orcid.org/0000-0002-3313-430X
Logan D SchneiderGoogle, Mountain View, CA, United States.ORCID https://orcid.org/0000-0001-8729-5224
Evan L BrittainVanderbilt University Medical Center, Nashville, TN, United States.ORCID https://orcid.org/0000-0001-5843-3392

Funding

Technology to Empower Changes in Health (TECH) Network Participant Technologies CenterU24OD023176 · OD · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2016 to 2022
$204.7M
Precision Medicine Initiative Cohort Program BiobankU24OD023121 · OD · MAYO CLINIC ROCHESTER · PI CEKANOVA, MARIA, CICEK, MINE · 2016 to 2024
$185.5M
Enhancing All of Us Data Resources for Nutrition Precision Health: the All of Us Data and Research CenterU2COD023196 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GLAZER, DAVID, HARRIS, PAUL A. · 2016 to 2022
$143.7M
Adaptive Platform for Personalized EngagementU24OD023163 · OD · VIGNET, INC. · PI JAIN, PRADUMAN · 2017 to 2020
$102.6M
University of Arizona-Banner Health All of Us Research Program OT2OD026549 · OD · UNIVERSITY OF ARIZONA · PI MORENO, FRANCISCO A, REIMAN, ERIC MICHAEL · 2018 to 2023
$78.9M
California Precision Medicine Research Program ConsortiumOT2OD026552 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANTON-CULVER, HODA A, OHNO-MACHADO, LUCILA · 2018 to 2023
$73.4M
All of Us PennsylvaniaOT2OD026554 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E, VISWESWARAN, SHYAM · 2018 to 2023
$72.1M
New York City Consortium for Precision MedicineOT2OD026556 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BIER, LOUISE E, GHARAVI, ALI G · 2018 to 2023
$67.3M
SouthEast Enrollment Center (SEEC) OT2OD026551 · OD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, COLON, VIVIAN · 2018 to 2023
$62.8M
Southern All of Us NetworkOT2OD026548 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N., KORF, BRUCE R · 2018 to 2023
$60.5M
Illinois Precision Medicine Consortium OT2OD026557 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AHSAN, HABIBUL, ARGOS, MARIA · 2018 to 2023
$60.5M
The New England Precision Medicine Consortium of the All of Us Research ProgramOT2OD026553 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CLARK, CHERYL RENEE, KARLSON, ELIZABETH W · 2018 to 2023
$58.8M
FDA HHS R01 FD007627NHLBI NIH HHS R21 HL172038NHLBI NIH HHS R33 HL158941NHLBI NIH HHS R61 HL158941NIH HHS OT2 OD023205NIH HHS OT2 OD023206NIH HHS OT2 OD025276NIH HHS OT2 OD025277NIH HHS OT2 OD025315NIH HHS OT2 OD025337NIH HHS OT2 OD026548NIH HHS OT2 OD026549NIH HHS OT2 OD026550NIH HHS OT2 OD026551NIH HHS OT2 OD026552NIH HHS OT2 OD026553NIH HHS OT2 OD026554NIH HHS OT2 OD026555NIH HHS OT2 OD026556NIH HHS OT2 OD026557NIH HHS U24 OD023121NIH HHS U24 OD023163NIH HHS U24 OD023176NIH HHS U2C OD023196
6 · The paper itself

Abstract

backgroundCommercial wearables such as Fitbit quantify sleep metrics using fixed calendar times as default measurement periods, which may not adequately account for individual variations in sleep patterns. To address this limitation, experts in sleep medicine and wearable technology developed a user-centric algorithm designed to more accurately reflect actual sleep behaviors and improve the validity of wearable-derived sleep metrics.

objectiveThis study aims to describe the development of a new user-centric algorithm, compare its performance with the default calendar-relative algorithm, and provide a practical guide for analyzing All of Us Fitbit sleep data on a cloud-based platform.

methodsThe default and user-centric algorithms were implemented to preprocess and compute sleep metrics related to schedule, duration, and disturbances using high-resolution Fitbit sleep data from 8563 participants (median age 58.1 years, 6002/8341, 71.96%, female) in the All of Us Research Program (version 7 Controlled Tier). Variations in typical sleep patterns were calculated by examining the differences in the mean number of primary sleep logs classified by each algorithm. Linear mixed-effects models were used to compare differences in sleep metrics across quartiles of variation in typical sleep patterns.

resultsOut of 8,452,630 total sleep logs collected over a median of 4.2 years of Fitbit monitoring, 401,777 (4.75%) nonprimary sleep logs identified by the default algorithm were reclassified as primary sleep by the user-centric algorithm. Variation in typical sleep patterns ranged from -0.08 to 1. Among participants with the greatest variation in typical sleep patterns, the user-centric algorithm identified significantly more total sleep time (by 17.6 minutes; P<.001), more wake after sleep onset (by 13.9 minutes; P<.001), and lower sleep efficiency (by 2.0%; P<.001), on average. Differences in sleep stage metrics between the 2 algorithms were modest.

conclusionsThe user-centric algorithm captures the natural variability in sleep schedules, providing an alternative approach to preprocess and evaluate sleep metrics related to schedule, duration, and disturbances. A publicly available R package facilitates the implementation of this algorithm for clinical and translational research.

Indexed as

AlgorithmsSleepWearable Electronic DevicesAdultAgedFemaleHumansLongitudinal StudiesMaleMiddle AgedRetrospective StudiesUnited StatesalgorithmsAll of Us Research ProgramFitbitmetricsR packagesleep

Identifiers

PMID40720818
PMCPMC12340457

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.