ArticlePLoS neglected tropical diseases2025
Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape.
Article in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape.PLoS neglected tropical diseases · 2025Article
- A systematic review on factors influencing immunisation adherence among children under 12 years of age.Health SA = SA Gesondheid · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
Spatio-temporal variations in environmental and socio-agricultural factors create heterogeneity in livestock disease transmission risk, raising challenges in identifying populations most at risk and how this risk changes over time. Consequently, effective vaccination strategies require careful planning to achieve optimal or equitable outcomes across regions. We developed a metapopulation model for Rift Valley fever transmission in livestock across the Comoros archipelago which incorporates livestock vaccination in addition to heterogeneity in viral transmission rates and animal movements. We used the model to evaluate three vaccine allocation strategies-proportional allocation, optimal allocation for maximising total infections averted across the archipelago, and optimal allocation for more equitable outcomes across islands-under different vaccination coverage levels and animal identification scenarios. We report that (i) both archipelago-wide and island-specific strategy effectiveness were impacted by vaccination rate, allocation strategy, and animal identification approach, (ii) optimally allocating vaccines improved strategy effectiveness compared with proportional allocation but resulted in inequitable outcomes between islands, and (iii) tagging animals post-vaccination boosted overall strategy effectiveness for all vaccination rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.