Evidence map›Paper›PMID 40720250›Full record

Trial reportClinical and translational science2025

Effects of Esketamine Combined With Remimazolam Tosylate on Hemodynamics During Cardiovascular Anesthesia.

Lei Xi, Hui Liu, XiaoJuan Tang, ZhenZhen Jiang

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lei XiDepartment of Anesthesiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, People's Republic of China.
Hui LiuDepartment of Anesthesiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, People's Republic of China.
XiaoJuan TangDepartment of Radiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, People's Republic of China.
ZhenZhen JiangDepartment of Anesthesiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effects of esketamine combined with remimazolam tosylate on hemodynamic stability, cerebral oxygen metabolism, and cognitive outcomes in patients undergoing heart valve replacement. Seventy-eight patients were randomized to Group C (dexmedetomidine hydrochloride) or Group R (esketamine + remimazolam tosylate). The following parameters were measured: multiple time points, including mean arterial pressure (MAP), heart rate (HR), respiratory rate (RR), arterial-jugular vein oxygen content difference (Da-jvO

Indexed as

BenzodiazepinesHeart Valve Prosthesis ImplantationHemodynamicsKetamineAdultAgedBiomarkersCardiopulmonary BypassCognitionDexmedetomidineDrug Therapy, CombinationFemaleHeart RateHumansMaleMiddle AgedBenzodiazepinesBiomarkersDexmedetomidineEsketamineKetamineOxygenremimazolamesketamineheart valve replacementhemodynamicsremimazolam tosylate

Identifiers

PMID40720250
PMCPMC12302974

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.