Evidence map›Paper›PMID 40720162›Full record

ArticleEuropean heart journal. Quality of care & clinical outcomes2026

Determinants of symptom relief and quality of life improvement after atrial fibrillation ablation.

Mark J Mulder, Michiel J B Kemme, Nikki van Pouderoijen, Luuk H G A Hopman, Marthe J Huntelaar, Herbert A Hauer, Giovanni J M Tahapary, Albert C van Rossum, Cornelis P Allaart

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Article in European heart journal. Quality of care & clinical outcomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Mark J MulderDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Michiel J B KemmeDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.ORCID 0000-0002-3671-5660
Nikki van PouderoijenDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Luuk H G A HopmanDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.ORCID 0000-0002-3896-9920
Marthe J HuntelaarDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Herbert A HauerDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Giovanni J M TahaparyDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.
Albert C van RossumDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.ORCID 0000-0003-1714-4652
Cornelis P AllaartDepartment of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, De Boelelaan 1117, 1081HV Amsterdam, The Netherlands.ORCID 0000-0002-0506-9512

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe primary goal of atrial fibrillation (AF) ablation is to improve AF-related symptoms and quality of life. Previous studies have observed a discrepancy between objective recurrence of AF after ablation and patient-perceived change of symptoms. Although predictors of freedom of AF recurrence after AF ablation have been widely studied, factors associated with symptom relief and quality of life improvement remain underexplored. The present study aimed to investigate determinants of symptom reduction and improvement in quality of life after AF ablation. METHODS AND

resultsA total of 382 AF patients (68% paroxysmal AF, 67% male, mean age 63 ± 9 years) undergoing AF ablation were included. Patient-reported outcomes were assessed using the Toronto Atrial Fibrillation Severity Scale (AFSS) and 36-Item Short-Form Health Survey (SF-36) score. Patients completed both the AFSS and SF-36 score pre-ablation, and post-ablation at 4 months and 1 year follow-up. Atrial tachyarrhythmia recurrence was documented in 139 patients (36%) at 1 year follow-up. AF symptom severity, patient-perceived AF burden and quality of life improved from baseline to 1 year follow-up, particularly in patients without atrial tachyarrhythmia recurrence. Greater baseline AFSS-derived symptom severity and patient-perceived AF burden were associated with a greater improvement of AF symptom severity and patient-perceived AF burden after ablation.

conclusionThis study shows that patients with lower quality of life and greater AF symptom severity and patient-perceived AF burden benefit most from AF ablation, suggesting that more emphasis should be put on the burden of AF symptoms in clinical decision-making.

Indexed as

Atrial FibrillationCatheter AblationQuality of LifeAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient Reported Outcome MeasuresRecurrenceSeverity of Illness IndexTreatment OutcomeAtrial fibrillationCatheter ablationPatient-related outcome measurePulmonary vein isolationSymptoms

Identifiers

PMID40720162
PMCPMC12770903

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