Evidence map›Paper›PMID 40720125›Full record

ArticleJAMA network open2025

Outcomes for Black and White Patients After Certification of Nearby Stroke Centers.

Yu-Chu Shen, Anthony S Kim, Renee Y Hsia

Abstract readMulticenter Study
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yu-Chu ShenDepartment of Defense Management, Naval Postgraduate School, Monterey, California.
Anthony S KimUCSF Weill Institute of Neurosciences, Department of Neurology, University of California, San Francisco.
Renee Y HsiaDepartment of Emergency Medicine, University of California, San Francisco.

Funding

NBER Center for Aging and Health Research-Post COVID-19 Experiences Among Adults with ADRDP30AG012810 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI DAVID M CUTLER · 1999 to 2026
$24.6M
Structural Racism and Discrimination in the Expansion of Hospital Stroke Care Capacity: A Multi-Level Analysis on Access to Care, Treatment, and OutcomesR01MD017482 · NIMHD · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI HSIA, RENEE YUEN-JAN, SHEN, YU-CHU · 2022 to 2025
$2.2M
NIA NIH HHS P30 AG012810NIMHD NIH HHS R01 MD017482
6 · The paper itself

Abstract

Importance: It is unclear whether stroke center certification near a community is associated with similar benefits for Black and White patients. Objective: To assess changes in admission to stroke centers, receipt of acute stroke treatment, and health outcomes for Black compared with White patients after the certification of a new stroke center near their community. Design, Setting, and Participants: This cohort study comprises Medicare fee-for-service patients from urban US communities with a primary diagnosis of acute ischemic stroke between January 1, 2009, and December 31, 2019, and compares changes in outcomes. Statistical analysis was performed from September 2024 to April 2025. Exposure: When a patient's community was exposed to the certification of a nearby stroke center relative to a patient of the same self-reported race in a community that was not exposed to a stroke center certification. Main Outcomes and Measures: A difference-in-differences framework was used to compare changes in (1) stroke center admission, (2) receipt of acute stroke treatments (thrombolytics and thrombectomy), and (3) health outcomes (home at 90 days and 1-year mortality) among Black and White patients. The empirical model was a linear probability model with community fixed effects. Results: This study included 2.1 million patients with stroke (15% Black patients and 85% White patients; 57% women; 15% aged 65-69 years, 16% aged 70-74 years, 18% aged 75-79 years, 19% aged 80-84 years, and 32% aged ≥85 years). After a newly certified stroke center opened near a community, the probability of admission to the stroke center increased for both White patients (15.6 percentage points [pp]; 95% CI, 14.6-16.6 pp) and Black patients (14.6 pp; 95% CI, 13.2-15.9 pp). Thrombolytic therapy increased for White patients by 0.2 pp (95% CI, 0.0-0.4 pp) but decreased for Black patients by 0.4 pp (95% CI, -0.7 to -0.1 pp) compared with their control communities. Black patients also had a 0.5-pp decrease in thrombectomy (95% CI, -0.6 to -0.3 pp). One-year mortality remained stable for White patients, while mortality for Black patients increased by 0.5 pp (95% CI, 0.1-0.9 pp). Conclusions and Relevance: This cohort study of 2.1 million patients with stroke found that stroke center certification near a community was associated with similar increases in rates of admission to the stroke center for Black and White patients, but it was associated with increased rates of receiving thrombolytics only for White patients. Thrombolysis and thrombectomy rates did not increase for Black patients who were exposed to a newly certified stroke center nearby. This study suggests that, despite the expansion of certified stroke centers, disparities in stroke care between Black and White patients persist.

Indexed as

Black or African AmericanCertificationIschemic StrokeStrokeWhiteAgedAged, 80 and overCohort StudiesFemaleHealthcare DisparitiesHumansMaleMedicareThrombolytic TherapyUnited States

Identifiers

PMID40720125
PMCPMC12305387

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.