ArticleThe Saudi dental journal2025
Antimicrobial efficacy of blueM gel and calcium hydroxide against F. nucleatum and E. faecalis biofilm: an ex-vivo study.
Article in The Saudi dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Modulating the periodontal wound microenvironment through oxygen therapy: a narrative review on the biological basis, clinical applications and future perspectives.The Saudi dental journal · 2026Review
- An Oxygen-Releasing Mouthwash Reduces Porphyromonas gingivalis Biofilm and Suppresses fimA and hagA Expression.International dental journal · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endodontic treatment failure can result from persistent bacteria, inadequate cleaning and sealing of root canals, and missed canals. The resilience of bacteria such as F. nucleatum and E. faecalis within the root canal system is a significant cause of failed endodontic treatment. Calcium hydroxide (CaOH), a widely utilized intracanal medicament, has demonstrated antimicrobial properties. However, its ability to consistently achieve culture-negative root canals after chemo-mechanical procedures remains inconsistent. This study aimed to evaluate and compare the antimicrobial efficacy of CaOH and BlueM gel against F. nucleatum and E. faecalis biofilms using dentin discs. Sterilized dentin discs were prepared from extracted human teeth. F. nucleatum and E. faecalis were grown on these discs and then treated with either CaOH or BlueM gel. Antimicrobial efficacy was assessed by quantifying colony-forming unit counts. BlueM gel demonstrated significantly greater antimicrobial efficacy than CaOH against both F. nucleatum and E. faecalis biofilms. Both agents exhibited substantial antimicrobial activity against the biofilms. BlueM gel showed superior antimicrobial effectiveness against endodontic pathogens such as F. nucleatum and E. faecalis compared to CaOH.
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Registered trials
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