ArticleBiometals : an international journal on the role of metal ions in biology, biochemistry, and medicine2025
Copper speciation in dairy cattle with different productivity levels.
Article in Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
There are almost no studies in the field of speciation of trace elements in the body of farm animals, in particular cattle. In this regard, the purpose of this study was to examine the species composition of copper in dairy cows depending on their productivity level. From the total number of Red Steppe breed cows (n = 90), 2 groups were formed: cows with low-normal milk yield values (n = 17)-group I (low-productive animals, average daily milk yield up to the 25th percentile); cows with high-normal values (n = 23)-group II (highly productive animals, average daily milk yield above the 75th percentile). Regardless of the productivity level, the content of chemical elements in the blood serum was in the range of normal physiological values. However, it was reliably established that highly productive animals had lower potassium levels and higher levels of phosphorus and copper relative to low-producing animals. The results of speciation analysis showed four copper-containing fractions in the blood serum of cows: transcuprein, ceruloplasmin, albumin and low-molecular forms of copper. Copper in the blood serum of cows of the Red Steppe breed, regardless of the level of productivity, is predominantly associated with albumin and ceruloplasmin (up to 90%). The rest of the copper was bound to transcuprein and low-molecular complexes (about 10%). When the level of total copper in the blood serum was up to 900 μg/L (0.9 μg/ml), the albumin fraction predominated over ceruloplasmin, and low-molecular-weight complexes prevailed over transcuprein. However, with an increase in the level of total copper above 900 μg/L (0.9 μg/ml), a shift occurred in the protein fractions; the ceruloplasmin fraction began to predominate over the albumin fraction, and transcuprein over low-molecular-weight complexes. In addition, a significant positive statistically significant association was identified between the total content of copper and ceruloplasmin in the blood with the average daily milk yield (r = 0.47; p < 0.05). The obtained data demonstrate the features of copper redistribution in cows of the Red Steppe breed, which can be used for an expanded assessment of the microelement status of animals, and, possibly, for predicting their productive qualities.
Indexed as
Identifiers
40720001What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.