Evidence map›Paper›PMID 40719948›Full record

SynthesisNeurosurgical review2025

Efficacy and safety of The Robotic Stereotactic Assistance for intracerebral hemorrhage; A systematic review and meta-analysis.

Mohamed Diaa Elfakhrany, Nada Mostafa Al-Dardery, Sadil Mohammad Bani Khaled, Mohamed El-Samahy, Shahd Alqato, Suhel F Batarseh, Ahmed Taha Abdelsattar, Mohamed Abouzid

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohamed Diaa Elfakhrany *Neurosurgery Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Nada Mostafa Al-Dardery *Faculty of Medicine, Fayoum University, Fayoum, Egypt. Ndardery449@gmail.com.
Sadil Mohammad Bani KhaledFaculty of Medicine, The University of Jordan, Amman, Jordan.
Mohamed El-SamahyFaculty of Medicine, Zagazig University, Zagazig, Egypt.
Shahd AlqatoInternal Medicine Department, Arab Medical Center, Amman, Jordan.
Suhel F BatarsehFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Ahmed Taha AbdelsattarFaculty of Medicine, Fayoum University, Fayoum, Egypt.
Mohamed AbouzidDepartment of Histology and Embryology, Poznan University of Medical Sciences, Poznan, Poland. mmahmoud@ump.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracerebral hemorrhage (ICH) is a critical medical condition associated with a high mortality rate. Surgical evacuation of extensive hemorrhage can improve survival and functional outcomes, but deep brain location poses a challenge. Our study seeks to provide robust evidence highlighting the efficacy, safety, and contribution of Robotic Stereotactic Assistance (ROSA) in advancing neurosurgical practices in the evacuation of ICH compared to conventional treatment methods. We searched for relevant papers comparing ROSA with conventional treatments until October 2024, using four electronic databases: PubMed, Scopus, the Cochrane Library, and Web of Science. The analysis was done using R Software. Continuous data was pooled as mean difference (MD), and dichotomous data was pooled as odds ratio (OR) in a random effect model with a relative 95% CI. A sub-group analysis was conducted according to the type of conventional therapy and the site of the hemorrhage. Eleven studies, comprising 968 patients (478 in the ROSA group and 490 in the control group "non-ROSA"), were included in the systematic review and meta-analysis. The analysis of primary outcomes revealed significantly higher postoperative Glasgow Coma Scale (GCS) scores, MD of 1.80 (95% CI: 0.68 to 2.92; p < 0.01), and lower rebleeding rates, OR of 0.26 (95% CI: 0.10 to 0.66; p < 0.01). However, no significant difference in mortality was found between the two groups, with an OR of 0.38 (95% CI: 0.11 to 1.38; p = 0.14). Regarding secondary outcomes, the ROSA group significantly reduced surgery duration and decreased intracranial infections and pneumonia. No significant difference was observed between the groups concerning central hypothermia. Using the ROSA robotic system for ICH evacuation is associated with improved neurological outcomes. These findings highlight the potential benefits of ROSA in advancing neurological practices for the management of ICH.

Indexed as

Cerebral HemorrhageNeurosurgical ProceduresRobotic Surgical ProceduresStereotaxic TechniquesHumansTreatment OutcomeGCSIntracerebral haemorrhageRebleedingROSA

Identifiers

PMID40719948
PMCPMC12304042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.