Evidence map›Paper›PMID 40719946›Full record

ReviewRice (New York, N.Y.)2025

Amino Acid Regulation in Rice: Integrated Mechanisms and Agricultural Applications.

Hangfei Luo, Bowen Wu, Bakht Amin, Jiaxu Li, Zhongbo Chen, Jian Shi, Weiting Huang, Zhongming Fang

Abstract readReview
In one paragraph

Review in Rice (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Genome-Wide Analysis of thePlants (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hangfei Luo *Institute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Bowen Wu *Institute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Bakht Amin *Institute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Jiaxu LiInstitute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Zhongbo ChenInstitute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Jian ShiInstitute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Weiting HuangInstitute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China.
Zhongming FangInstitute of Rice Industry Technology Research, Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions, Key Laboratory of Molecular Breeding for Grain and Oil Crops in Guizhou Province, Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region (Ministry of Education), College of Agricultural Sciences, Guizhou University, Guiyang, 550025, China. zmfang@gzu.edu.cn.

Funding

Guizhou Provincial Excellent Young Talents Project of Science and Technology qiankehepingtairencai-YQK (2023) 002Key Laboratory of Functional Agriculture of Guizhou Provincial Higher Education Institutions Qianjiaoji (2023) 007National Natural Science Foundation of China 32260498Science and Technology Program of Guizhou Province qiankehejichu-ZK (2022) Key 008; qiankehechengguo (2024) general 116; Qiankehepingtairencai-BQW (2024) 001
6 · The paper itself

Abstract

This review synthesizes how amino acid (AA) metabolism regulates rice stress tolerance, growth and quality through stress protection and growth-modulating pathways, bridging mechanisms to field applications. Under abiotic stresses, rice accumulates specific AAs-notably proline (Pro), γ-aminobutyric acid (GABA), and branched-chain AAs (BCAAs)-as osmoprotectants and antioxidants, correlating strongly with stress tolerance. Genetic evidence establishes causality: overexpression of biosynthetic genes (e.g., OsOAT for Pro, OsDIAT for BCAAs), while suppressing catabolism (e.g., OsProDH knockout) or engineering AA transporters (AATs) (e.g., ABA-induced OsANT1 for amino acids redistribution) enhances tolerance. Integrated AA biosynthetic, catabolic, and transport pathways collectively maintain cellular function under stress. These insights enable practical strategies: exogenous AA treatments (e.g., Pro, GABA) mitigate stress damage, while breeding/engineering (e.g., OsAAP3, OsAAP11, and OsProDH knockout) develops high-yield, high-quality, and stress-tolerant rice. Future work should translate molecular insights into field applications, addressing trade-offs between growth, nutrition, and tolerance to enhance climate-resilient rice production.

Indexed as

Agricultural BiotechnologyAmino AcidGenetic EngineeringRiceStress ToleranceTransporters

Identifiers

PMID40719946
PMCPMC12304346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.