Evidence map›Paper›PMID 40719933›Full record

ArticleOral and maxillofacial surgery2025

Black bone and CT-like MRI-based delineation of fracture-prone regions in oral and maxillofacial trauma.

Adib Al-Haj Husain, Peter Kessler, Suen An Nynke Lie, Samuel Drack, Egon Burian, Sameena Sandhu, Maximilian Eberhard Hermann Wagner, Bernd Stadlinger, Thomas Frauenfelder, Giovanni Colacicco and 2 more

Abstract read
In one paragraph

Article in Oral and maxillofacial surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Adib Al-Haj HusainDepartment of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. adib.al-hajhusain@usz.ch.ORCID http://orcid.org/0000-0001-7895-1461
Peter KesslerDepartment of Cranio-Maxillofacial Surgery, GROW School for Oncology and Reproduction, Maastricht University Medical Centre, Maastricht, The Netherlands.
Suen An Nynke LieDepartment of Cranio-Maxillofacial Surgery, GROW School for Oncology and Reproduction, Maastricht University Medical Centre, Maastricht, The Netherlands.
Samuel DrackDepartment of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Egon BurianDiagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Sameena SandhuDepartment of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Maximilian Eberhard Hermann WagnerDepartment of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Bernd StadlingerClinic of Cranio-Maxillofacial and Oral Surgery, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.
Thomas FrauenfelderDiagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Giovanni ColaciccoInstitute of Anatomy, University of Zurich, Zurich, Switzerland.
Rubens Spin-NetoOral Radiology, Department of Dentistry and Oral Health, Aarhus University, Aarhus C, Denmark.
Harald EssigDepartment of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the effectiveness and feasibility of MRI-based delineation of fracture-prone regions in the oral and maxillofacial region using Black Bone and CT-like MRI protocols optimized for dentomaxillofacial imaging with a dedicated 15-channel mandibular coil.

methodsIn this prospective study, healthy volunteers underwent 3T MRI using five protocols: DESS, SPACE STIR, SPACE SPAIR, T1-VIBE Dixon, and UTE. Eight trauma-prone regions, including the nasal septum, orbit, naso-orbito-ethmoidal (NOE) complex, zygomaticomaxillary complex, Le Fort regions, mandible, condyle, and dentoalveolar complex, were assessed. Image quality, artifacts, anatomical delineation, and bone-to-soft-tissue contrast were rated on a five-point Likert scale by three independent observers. Descriptive statistics and inter-rater agreement (intraclass correlation coefficients (ICCs)) were calculated.

resultsSixteen participants (37.2 ± 12.9 years; 12 males, 4 females) were included, resulting in 80 MRI volumes and 640 regions for evaluation. UTE and VIBE-DIXON sequences achieved the highest ratings for image quality, artifact susceptibility, and anatomical delineation across most fracture-prone regions (ICC: 0.793-1; all p < 0.001). UTE excelled in visualizing NOE and Le Fort regions, while VIBE-DIXON performed best in mandibular and orbital imaging. Bone-to-soft-tissue contrast was highest in UTE and VIBE-DIXON, highlighting their diagnostic potential in simultaneous soft and hard tissue imaging. Inter-rater agreement was consistently high (ICC: 0.772-0.976; all p < 0.001).

conclusionDedicated trauma-specific MRI protocols show promising potential as a radiation-free modality for maxillofacial trauma imaging, particularly in young adults and pediatric patients. The strengths of each protocol highlight the need for tailored sequence selection to optimize diagnostic accuracy and personalized care. TRIAL REGISTRATION NUMBER: Swiss National Clinical Trials Portal: SNCTP000005246.

Indexed as

Magnetic Resonance ImagingMaxillofacial InjuriesTomography, X-Ray ComputedAdultArtifactsFeasibility StudiesFemaleHealthy VolunteersHumansMaleMiddle AgedProspective StudiesBlack boneCT-like MRIDiagnostic imagingMagnetic resonance imagingMaxillofacial injuriesMaxillofacial surgery

Identifiers

PMID40719933
PMCPMC12304013

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.