Evidence map›Paper›PMID 40719913›Full record

ArticleCurrent microbiology2025

Comamonas resistens Co-Producing GES-5 and OXA-17 in Urban Wastewater as a Potential Novel Disseminator of Clinically Relevant β-Lactamases.

João Pedro Rueda Furlan, Giovanna Carrasco Bueno, Rubens Renato Sousa-Carmo, Renan Lourenço Oliveira Silva, Mikaela Renata Funada Barbosa, Maria Ines Zanoli Sato, Nilton Lincopan, Sergio Schenkman

Abstract read
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Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. First Report of a Carbapenem-ResistantInfection and drug resistance · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

João Pedro Rueda FurlanEscola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil. furlanjpr@gmail.com.ORCID http://orcid.org/0000-0003-2516-1129
Giovanna Carrasco BuenoEscola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Rubens Renato Sousa-CarmoDepartment of Microbiology, Instituto de Ciências Biomédicas, University of São Paulo, São Paulo, Brazil.
Renan Lourenço Oliveira SilvaDepartment of Environmental Analysis, Environmental Company of São Paulo State (CETESB), São Paulo, Brazil.
Mikaela Renata Funada BarbosaDepartment of Environmental Analysis, Environmental Company of São Paulo State (CETESB), São Paulo, Brazil.
Maria Ines Zanoli SatoDepartment of Environmental Analysis, Environmental Company of São Paulo State (CETESB), São Paulo, Brazil.
Nilton LincopanARIES, Antimicrobial Resistance Institute of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-0161-5800
Sergio SchenkmanEscola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil. sschenkman@unifesp.br.ORCID http://orcid.org/0000-0001-9353-8480

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 21/10599-3
6 · The paper itself

Abstract

Comamonas species have been isolated from different sources, with Comamonas testosteroni and Comamonas resistens commonly related to human diseases and multidrug resistance, respectively. During a surveillance study to monitor carbapenem resistance in bacteria from wastewater samples in Brazil, a carbapenem-resistant strain, named M13, was obtained and identified as C. resistens (ANI 98.90%, dDDH 94.60%) by genomic analysis, being a species distinct from C. testosteroni. It exhibited multidrug resistance and presented small inhibition zones around disks containing novel β-lactams and β-lactam-β-lactamase inhibitor combinations. Comparative genomics showed significant single nucleotide polymorphism divergence between M13 and other C. resistens genomes, suggesting geographically driven genomic diversity. Strain M13 uniquely harbored genes related to antimicrobial resistance and metal tolerance as follows: bla

Indexed as

Bacterial Proteinsbeta-LactamasesWastewaterAnti-Bacterial AgentsBrazilCarbapenemsDrug Resistance, Multiple, BacterialGenome, BacterialHumansMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCarbapenemsWastewater

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.