Evidence map›Paper›PMID 40719895›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

A review of the extraction technologies, structural characterization, chemical modification, and pharmacological effects of Ganoderma lucidum polysaccharides.

ChenXue Li, RuoBing Zhang, Bing Tian, Bing Liu, Yu Mei, WenLan Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. AClinical, cosmetic and investigational dermatology · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

ChenXue Li *Postdoctoral Station On Chinese Materia Medica of Harbin University of Commerce, Harbin, 150076, China.
RuoBing ZhangSchool of Pharmacy, Harbin University of Commerce, Harbin, 150076, China.
Bing TianSchool of Pharmacy, Harbin University of Commerce, Harbin, 150076, China.
Bing LiuSchool of Pharmacy, Harbin University of Commerce, Harbin, 150076, China.
Yu MeiSchool of Pharmacy, Harbin University of Commerce, Harbin, 150076, China.
WenLan Li *Postdoctoral Station On Chinese Materia Medica of Harbin University of Commerce, Harbin, 150076, China. li0104ok@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ganoderma lucidum (GL) is a medicinal and edible fungal material with a long history. Ganoderma lucidum polysaccharides (GLPs), as one of the primary bioactive components in GL, exhibit multiple pharmacological effects including anti-tumor, anti-inflammatory, immunomodulatory, antioxidant, and metabolic regulatory activities. While the monosaccharide composition and structural characteristics of GLPs are influenced by extraction methods and chemical modifications, the relationship between their structural features and bioactivities remains unclear. This review summarizes recent advances in the extraction, preparation, structural analysis, chemical modification, emerging technologies, and clinical applications of GLPs, providing insights for further exploration and elucidation of their structure-activity relationships. Additionally, the pharmacological potential of GLPs is systematically reviewed, highlighting their promising applications in pharmaceutical development and functional food innovation. This comprehensive analysis offers valuable references for advancing the utilization of GLPs in medicinal and nutraceutical fields.

Indexed as

Fungal PolysaccharidesPolysaccharidesReishiAnimalsHumansStructure-Activity RelationshipFungal PolysaccharidesPolysaccharidesDeep fermentationExtraction and isolationGanoderma lucidum polysaccharidePharmacological effectsStructural characteristics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.