Evidence map›Paper›PMID 40719880›Full record

ReviewDermatologie (Heidelberg, Germany)2025

[Common skin and soft tissue infections-current recommendations].

Cord Sunderkötter, Helena Schieffers, Karsten Becker, Jan Ehrchen

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Dermatologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. S1 Guideline on Infected Interdigital Intertrigo (also called Gram-Negative Toe Web Infection).Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Guideline
  2. Article
  3. Article
  4. Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis - a monocentric, retrospective, explorative study.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cord SunderkötterUniversitätsklinik und Poliklinik für Dermatologie und Venerologie, Universitätsmedizin Halle, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland. cord.sunderkoetter@uk-halle.de.
Helena SchieffersUniversitätsklinik und Poliklinik für Dermatologie und Venerologie, Universitätsmedizin Halle, Martin-Luther-Universität Halle-Wittenberg, Ernst-Grube-Str. 40, 06120, Halle (Saale), Deutschland.
Karsten BeckerFriedrich Loeffler-Institut für Medizinische Mikrobiologie, Universitätsmedizin Greifswald, Greifswald, Deutschland.
Jan EhrchenKlinik für Hautkrankheiten-Allgemeine Dermatologie und Venerologie, Universitätsklinikum und Medizinische Fakultät Münster, Münster, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abscesses, erysipelas, or uncomplicated skin and soft tissue infections (phlegmons) are common soft tissue infections encountered by dermatologists. Their definition, diagnosis, and treatment are summarized here based on the updated German-language guidelines. Cutaneous abscesses are encapsulated, pus-filled cavities which, depending on their location in deep or superficial skin-layers, cause solid to fluctuating, more or less erythematous, painful swelling under usually intact epidermis. Superficial and mature abscesses reveal visible collection of pus. Primary and often sufficient therapy consists of incision and drainage. In the presence of complicating factors, an antibiotic targeting Staphylococcus (S.) aureus is additionally recommended. Erysipelas, caused by streptococci, is characterized by bright-red, often shiny erythema with sometimes arched margins, which is initially accompanied by constitutional symptoms such as shivers or fever. The treatment of choice is penicillin. An uncomplicated soft tissue infection is usually caused by S. aureus and is characterized by a livid red erythema with slight edema and blurred margins. Constitutional symptoms do not generally occur and sometimes only in the course of infection. They are sufficiently treated with, e.g., oral cefadroxil or intravenous cefazolin. Complicated soft tissue infections are extensive infections of soft tissue due to certain comorbidities, such as severe diabetes, immunosuppression, liver or kidney failure or to complicating factors such as burns or injuries with foreign bodies. The spectrum of causative bacteria is broader and must be considered for calculated antibiotic therapy. This review is intended to provide targeted and successful antibiotic therapy and to reduce adverse effects and development of resistant bacteria.

Indexed as

Practice Guidelines as TopicSkin Diseases, BacterialSoft Tissue InfectionsAbscessAnti-Bacterial AgentsErysipelasGermanyHumansAnti-Bacterial AgentsAbscessAntibioticsComplicated soft tissue infectionErysipelasUncomplicated soft tissue infection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.