ArticleExperimental physiology2026
Sex differences in loop gain measured via superimposed end-expiratory breath holds and inspired steady-state hypoxia.
Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Sex differences in loop gain measured via superimposed end-expiratory breath holds and inspired steady-state hypoxia.Experimental physiology · 2026Article
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4 authors.
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Abstract
Acute low oxygen exposure (hypoxia) elicits a hypoxic ventilatory response (HVR), which increases ventilation and mitigates hypoxaemia. During sustained exposure to hypoxia, ventilatory acclimatization increases peripheral chemoreflex (HVR) sensitivity or chemoreflex loop gain (LG). Although increased ventilation protects oxygenation, increased LG contributes to ventilatory instability during sleep (central sleep apnoea; CSA). The HVR is highly variable between individuals, and the impact of sex on HVR variability and LG is unclear. At low altitude (1100 m), we aimed to characterize a novel breath hold method to quantify LG using a standardized series of short (∼10 s), voluntary, end-expiratory breath holds (EEBH), using a background of steady-state normobaric inspired hyperoxia (fraction of inspired oxygen;
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