Evidence map›Paper›PMID 40719651›Full record

ArticleVeterinary medicine and science2025

Sero-Prevalence and Molecular Detection of Mycobacterium bovis in Cattle at Sylhet Division of Bangladesh.

Md Atik Faysal, Md Shahidur Rahman Chowdhury, Fatema Yeasmin Tanni, Hemayet Hossain, Khadiza Akter Brishty, Md Bashir Uddin, Md Masudur Rahman, Md Mahfujur Rahman, Md Mukter Hossain

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Md Atik FaysalDepartment of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.
Md Shahidur Rahman ChowdhuryDepartment of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.
Fatema Yeasmin TanniDepartment of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.
Hemayet HossainDepartment of Anatomy and Histology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.ORCID 0009-0007-4698-3128
Khadiza Akter BrishtyDepartment of Zoology (GSSC), University of Dhaka, Dhaka, Bangladesh.
Md Bashir UddinDepartment of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.ORCID 0000-0002-0045-9669
Md Masudur RahmanDepartment of Pathology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.ORCID 0000-0003-2062-8471
Md Mahfujur RahmanDepartment of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.
Md Mukter HossainDepartment of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh.ORCID 0000-0002-8506-1202

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMycobacterium bovis, the cause of bovine tuberculosis (bTB), is a contagious, notifiable, chronic bacterial disease that causes economic losses. bTB remains a significant zoonotic threat, particularly in resource-limited settings where reliable prevalence data are still lacking.

objectivesThis study aimed to determine the serological prevalence and molecular detection of bTB from different commercial and individual dairy farms of Sylhet and Sunamganj districts in Bangladesh.

methodsA cross-sectional study was conducted on a total of 250 blood and 250 milk samples, which were collected across selected dairy farms. Serological testing was performed using indirect ELISA, and molecular detection of M. bovis was carried out through PCR. Associations between infection status and potential risk factors were evaluated using chi-square tests and logistic regression models.

resultsThe overall prevalence of M. bovis was 10.6%. Molecular detection through PCR revealed a higher prevalence in milk (14.8%) compared to blood (6.4%) samples. Serological testing showed that the prevalence in Sylhet district was lower (5.3%) than in Sunamganj district (12.0%). The highest prevalence was observed in diarrhoeic animals (19.49%), followed by female cattle (13.58%) and Holstein Friesian cows (14.0%). Cattle aged 1-3 years showed a notable prevalence of 17.51%.

conclusionsThe presence of M. bovis in dairy cattle herds was confirmed by both molecular and serological methods, highlighting the endemic nature of bTB in the study area. These findings underscore the importance of routine surveillance, combining diagnostic approaches and implementing effective control measures to reduce the burden of bTB in dairy production systems.

Indexed as

Mycobacterium bovisTuberculosis, BovineAnimalsBangladeshCattleCross-Sectional StudiesFemaleMaleMilkPolymerase Chain ReactionPrevalenceSeroepidemiologic Studiesantibodies | bovine tuberculosis | molecular detection | public health | serum ELISA

Identifiers

PMID40719651
PMCPMC12302530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.