Evidence map›Paper›PMID 40719548›Full record

ArticleHepatology communications2025

Integrating hepatology with addiction care for inpatients with alcohol use disorder reduces future liver-related events.

Paul George, Chantelle Marshall, Wei Zhang, Russell Goodman, Michael Butler, Suraj J Patel, Mack Mitchell, Esperance Schaefer, Jay Luther

Abstract read
In one paragraph

Article in Hepatology communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul GeorgeDepartment of Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Chantelle MarshallMGH Alcohol Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Wei ZhangMGH Alcohol Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Russell GoodmanMGH Alcohol Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Michael ButlerMGH Alcohol Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Suraj J PatelDivision of Gastroenterology, University of Texas at Southwestern, Dallas, Texas, USA.
Mack MitchellDivision of Gastroenterology, University of Texas at Southwestern, Dallas, Texas, USA.
Esperance SchaeferMGH Alcohol Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jay LutherMGH Alcohol Liver Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Integrated therapies for alcohol use and ALD (ITAALD) Network – UTSW Clinical CenterU01AA026975 · NIAAA · UT SOUTHWESTERN MEDICAL CENTER · PI E SHERWOOD BROWN, Mack Clarence Mitchell · 2018 to 2026
$3.0M
NIAAA NIH HHS U01 AA026975
6 · The paper itself

Abstract

backgroundStrategies to identify patients with early alcohol-associated liver disease (ALD), prior to the development of liver-related decompensated events, and promote alcohol therapy engagement in these patients are urgently needed to stem the rising tide of mortality associated with ALD.

methodsWe compared the rate of incident liver-related decompensating events in hospitalized patients with alcohol use disorder (AUD) seen either by an integrated hepatology and addiction care approach or addiction care alone at 2 academic medical centers. Cox proportional hazards regression model and a Kaplan-Meier analysis were used.

findingsAn integrated approach of hepatology and addiction care is associated with a reduced likelihood of future liver-related decompensating events in hospitalized patients with AUD. This finding correlated with an increased uptake of medical alcohol therapy and a reduced likelihood of an alcohol-associated readmission. Integrated hepatology and addiction care for hospitalized AUD patients may help reduce the progression of ALD.

Indexed as

Addiction MedicineAlcoholismDelivery of Health Care, IntegratedGastroenterologyLiver Diseases, AlcoholicAdultFemaleHospitalizationHumansInpatientsMaleMiddle AgedProportional Hazards Modelsalcohol useliver diseasemultidisciplinary

Identifiers

PMID40719548
PMCPMC12306700

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.