Evidence map›Paper›PMID 40719460›Full record

ArticlemSphere2025

The salivary virome during childhood dental caries.

Jonah Tang, Jonathon L Baker

Abstract read
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jonah TangDepartment of Biomaterial and Biomedical Sciences, OHSU School of Dentistry, Portland, Oregon, USA.
Jonathon L BakerDepartment of Biomaterial and Biomedical Sciences, OHSU School of Dentistry, Portland, Oregon, USA.ORCID 0000-0001-5378-322X

Funding

High Performance Computing and Machine Learning Infrastructure for Oregon Life SciencesS10OD034224 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLROTT, KYLE · 2023 to 2023
$2.0M
Investigating Membrane Alterations as a Mechanism of Acid Tolerance in Cariogenic BacteriaR00DE029228 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI BAKER, JONATHON · 2023 to 2025
$747k
NIDCR NIH HHS R00 DE029228NIDCR NIH HHS R00-DE029228NIH HHS S10 OD034224
6 · The paper itself

Abstract

While many studies have examined the bacterial taxa associated with dental caries, the most common chronic infectious disease, little is known about the caries-associated virome. In this study, the salivary viromes of 21 children with severe caries (>2 dentin lesions) and 23 children with healthy dentition were examined. A total of 2,485 viral metagenome-assembled genomes (vMAGs) were identified, binned, and quantified from the metagenomic assemblies. These vMAGs were mostly phages and represented 1,865 unique species-level viral operational taxonomic units (vOTUs), of which 478 appear to be novel. The metagenomes were also queried for all 3,858 unique species-level vOTUs of DNA viruses with a human host on NCBI Virus; however, all but

Indexed as

Dental CariesSalivaViromeVirusesBacteriaBacteriophagesChildChild, PreschoolFemaleGenome, ViralHumansMaleMetagenomeMetagenomicsMicrobiotabacteriophagesdental cariesoral microbiome

Identifiers

PMID40719460
PMCPMC12379589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.