ArticleFrontiers in oncology2025
Baseline MRI habitat imaging for predicting treatment response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
9 authors.
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Abstract
Purpose: This study was to assess whether baseline magnetic resonance habitat imaging can predict the efficacy of neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC). Methods: This retrospective study analyzed data from 181 patients with locally advanced rectal cancer, including 60 who exhibited a good treatment response. The cohort was randomly divided into a training set (127 patients, 42 with good response) and a validation set (54 patients, 18 with good response). Five models were developed: Model Results: The AUC values for predicting the efficacy of LARC neoadjuvant therapy were as follows: in the training set, Model Conclusion: The habitat model we developed, which integrates first-order and clinical features, demonstrates potential for predicting the efficacy of nCRT clinically interpretable spatial heterogeneity information. This model may aid in personalized treatment decision-making for LARC.
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