Evidence map›Paper›PMID 40718812›Full record

ReviewFrontiers in microbiology2025

Respiratory microbiota, host immunity, respiratory viral infections and malignant tumors.

Xinjie Jiang, Sujiang Zhang

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Xinjie JiangCollege of Life Sciences and Technology, Tarim University, Alar, China.
Sujiang ZhangCollege of Life Sciences and Technology, Tarim University, Alar, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the role of the respiratory tract microbiota in respiratory tract infections has attracted considerable attention. Respiratory microbiota have important effects on respiratory physiology, immune regulation, and the occurrence and development of various respiratory viral infectious diseases. The microbial composition in the different parts of the respiratory tract, such as the nose, oropharynx, and lower respiratory tract, varies. Under physiological conditions, the respiratory microbiota remains relatively stable; however, when this homeostatic balance is disrupted, respiratory microbiota imbalance occurs, increasing the risk of infection. An increasing number of studies have revealed the complex relationship between bacterial dysregulation and respiratory viral infections. Dysregulation of the respiratory tract microbiota plays an important role in both innate and adaptive immune responses. In this study, changes in respiratory microbes and their interactions with host immunity, respiratory viral infections and malignant tumors were reviewed. Future studies should further explore the interaction mechanism between respiratory microbiota and host immunity, develop new diagnostic and therapeutic strategies, and improve the current level of clinical treatment for respiratory diseases.

Indexed as

airway dysbiosisimmuneinteractionrespiratory tract microbiotaviral infection

Identifiers

PMID40718812
PMCPMC12291555

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.