Evidence map›Paper›PMID 40718701›Full record

ReviewBurns & trauma2025

Bioprinting vascularized skin analogs: a stepwise approach.

Linyang Liu, Eugenia Spessot, Khoon S Lim, Ziyu Wang, Suzanne M Mithieux, Devid Maniglio, Antonella Motta, Anthony S Weiss

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Burns & trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linyang LiuSchool of Life and Environmental Sciences, University of Sydney, Building D17 New South Wales, 2006, Australia.
Eugenia SpessotBIOtech Research Centre, Department of Industrial Engineering, Via delle Regole 101, 38123, University of Trento, Trento, Italy.
Khoon S LimCharles Perkins Centre, University of Sydney, Building D17, New South Wales, 2006, Australia.
Ziyu WangSchool of Life and Environmental Sciences, University of Sydney, Building D17 New South Wales, 2006, Australia.
Suzanne M MithieuxSchool of Life and Environmental Sciences, University of Sydney, Building D17 New South Wales, 2006, Australia.
Devid ManiglioBIOtech Research Centre, Department of Industrial Engineering, Via delle Regole 101, 38123, University of Trento, Trento, Italy.
Antonella MottaBIOtech Research Centre, Department of Industrial Engineering, Via delle Regole 101, 38123, University of Trento, Trento, Italy.
Anthony S WeissSchool of Life and Environmental Sciences, University of Sydney, Building D17 New South Wales, 2006, Australia.ORCID https://orcid.org/0000-0002-8106-4836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioprinting has emerged as a promising technology for fabricating vascularized skin substitutes. The availability of functional skin tissue constructs is critical for the surgical treatment of various wounds, including ulcers and burns. Integrating functional vascular networks within engineered skin constructs is indispensable for ensuring adequate nutrient perfusion and overall tissue viability. This review undertakes a comprehensive exploration of the application of 3D bioprinting for fabricating vascularized skin tissue constructs. It encompasses an examination of the printing modalities, ink formulations, and cell-sourcing strategies currently prevalent in the field. The design and formulation of suitable inks are crucial steps in the successful bioprinting of vascularized skin constructs, and various ink components such as biomaterials, cells, growth factors, and bioactive molecules are particularly considered, with a focus on their roles in promoting angiogenesis and blood vessel formation within the printed constructs.

Indexed as

BioinksBioprintingSkinVascularization

Identifiers

PMID40718701
PMCPMC12291544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.