Evidence map›Paper›PMID 40718681›Full record

ArticleFrontiers in cellular and infection microbiology2025

The global proteome of

Supradipta De, Larissa M Busch, Gerhard Burchhardt, Manuela Gesell Salazar, Rabea Schlüter, Leif Steil, Uwe Völker, Sven Hammerschmidt

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Microbiology spectrum · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Supradipta DeDepartment of Molecular Genetics and Infection Biology, Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
Larissa M BuschDepartment of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine, Greifswald, Germany.
Gerhard BurchhardtDepartment of Molecular Genetics and Infection Biology, Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.
Manuela Gesell SalazarDepartment of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine, Greifswald, Germany.
Rabea SchlüterImaging Center of the Department of Biology, University of Greifswald, Greifswald, Germany.
Leif SteilDepartment of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine, Greifswald, Germany.
Uwe VölkerDepartment of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine, Greifswald, Germany.
Sven HammerschmidtDepartment of Molecular Genetics and Infection Biology, Interfaculty Institute of Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: To investigate the molecular biology of Result: The optimized medium enhanced growth and shortened the lag phase of Discussion: These findings highlight dynamic proteomic changes associated with pneumococcal adaptation to nutrient-limited conditions and provide insights into the biology of strain EF3030 during colonization. The optimized medium offers a reproducible platform for studying pneumococcal physiology and pathogenesis under defined conditions.

Indexed as

Bacterial ProteinsProteomeStreptococcus pneumoniaeCulture MediaGene Expression Regulation, BacterialMembrane Transport ProteinsMethionineMicroscopy, Electron, ScanningPneumococcal InfectionsTrace ElementsVirulence FactorsBacterial ProteinsCulture MediaMembrane Transport ProteinsMethionineProteomeTrace ElementsVirulence Factorsbacterial morphologycompetenceinfection related conditionminimal growth mediumproteome analysisscanning electron microscopyStreptococcus pneumoniae

Identifiers

PMID40718681
PMCPMC12289677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.