Evidence map›Paper›PMID 40718680›Full record

ArticleFrontiers in cellular and infection microbiology2025

Exploratory analysis of potential association between oral

Yachen Shi, En Zhao, Weigang Gong, Qianqian Gao, Yang Li, Guangjun Xi, Yan Han, Hui Weng, Feng Wang, Feng Geng and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Potential value of oral Mogibacterium in major depressive disorder.Frontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yachen Shi *Department of Neurology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
En Zhao *Department of Gastroenterology, Xishan People's Hospital of Wuxi City, Wuxi, China.
Weigang Gong *Department of Neurology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Qianqian Gao *Department of Radiology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Yang LiDepartment of Neurology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Guangjun XiDepartment of Neurology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Yan HanDepartment of Neurology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Hui WengDepartment of Psychology and Sleep Medicine, The Second Hospital of Anhui Medical University, Hefei, China.
Feng WangDepartment of Neurology, the Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Feng GengDepartment of Psychology and Sleep Medicine, The Second Hospital of Anhui Medical University, Hefei, China.
Gaojia ZhangDepartment of Psychology and Sleep Medicine, The Second Hospital of Anhui Medical University, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The current study aimed to explore the specific oral microbiota profiles in major depressive disorder (MDD) patients with sleep disturbances, and to evaluate the potential mechanisms by which oral microbiota may be implicated in MDD. Method: Thirty-eight MDD patients experiencing sleep disturbances and thirty healthy controls (HCs) were included. All MDD patients underwent a 14-day antidepressive treatment regimen. Neuropsychological assessments were conducted, and 16S rRNA sequencing was used to determine the abundance of oral bacteria. Results: Oral genera Conclusion: Oral

Indexed as

HaemophilusMajor Depressive DisorderMouthSleep Wake DisordersAdultAntidepressive AgentsCase-Control StudiesDysbiosisFemaleHumansMaleMicrobiotaMiddle AgedRNA, Ribosomal, 16SAntidepressive AgentsRNA, Ribosomal, 16Sglial fibrillary acidic proteinhaemophilusmajor depressive disorderoral microbiotasleep disturbances

Identifiers

PMID40718680
PMCPMC12289620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.