Evidence map›Paper›PMID 40718614›Full record

ArticleEuroasian journal of hepato-gastroenterology

Deficiencies of Micronutrients in Potential Liver Transplant Candidates: A Cross-sectional Study.

Manesh Kumar, Zaigham Abbas, Darayus P Gazder, Shamim Nazir, Sania Maqbool, Muhammad A Qadeer

Abstract read
In one paragraph

Article in Euroasian journal of hepato-gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Micronutrient deficiencies in hepatic cirrhosis: Navigating challenges to assessment and implications for clinical management: A narrative review.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manesh KumarDepartment of Gastroenterology and Hepatology, Dr. Ziauddin University and Hospital, Karachi, Sindh, Pakistan.
Zaigham AbbasDepartment of Gastroenterology and Hepatology, Dr. Ziauddin University and Hospital, Karachi, Sindh, Pakistan.
Darayus P GazderDepartment of Gastroenterology and Hepatology, Dr. Ziauddin University and Hospital, Karachi, Sindh, Pakistan.
Shamim NazirDepartment of Gastroenterology and Hepatology, Dr. Ziauddin University and Hospital, Karachi, Sindh, Pakistan.
Sania MaqboolDepartment of Gastroenterology and Hepatology, Dr. Ziauddin University and Hospital, Karachi, Sindh, Pakistan.
Muhammad A QadeerDepartment of Gastroenterology and Hepatology, Dr. Ziauddin University and Hospital, Karachi, Sindh, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Decompensated liver disease is a debilitating condition often accompanied by significant micro- and macronutrient deficiencies, which can worsen prognosis and complicate treatment, particularly in potential liver transplant candidates. Objective: We aimed to identify nutritional deficiencies in patients with decompensated chronic liver disease (CLD), who are potential recipients for liver transplantation. Materials and methods: This cross-sectional, single-center prospective study included consecutive patients. Blood tests were performed to measure levels of key micronutrients, including vitamin D3, zinc, calcium, magnesium, phosphorus, iron, folic acid, and vitamin B12. Nutrient deficiencies were compared in patients with a model for end-stage liver disease (MELD) score ≥15 or less, and Child-Pugh class of B and C. Results: The cohort comprised a total of 116 patients, 79 (68.1%) males and 37 (31.9%) females. Sixty-nine patients (59.5%) were classified as Child-Pugh class B and 47 patients (40.5%) as Child-Pugh class C, and 71 (61.2%) patients had an MELD score of ≥15. The primary etiologies of CLD were hepatitis C [49 (42.2%)], non-alcoholic fatty liver disease [30 (25.9%)], alcoholic liver disease [20 (17.2%)], hepatitis B [11 (9.5%)], and autoimmune liver disease [6 (5.2%)]. The study identified higher frequencies of deficiencies in zinc (89.7%), vitamin D3 (deficient 62.1%, insufficient 23.3%), calcium (18.1%), folate (15.5%), magnesium (14.7%), iron (13.8%), phosphorus (10.3%), and vitamin B12 (5.2%) across the entire cohort. Vitamin D and magnesium deficiencies became more frequent in Child-Pugh class C compared to B ( Conclusion: The high prevalence of deficiencies of crucial micronutrients, such as vitamin D3, zinc, magnesium, and iron highlighted the necessity of comprehensive assessments of nutrition and targeted intervention in patients with decompensated CLD. Effective management of micronutrient levels could potentially reduce complications, improve patient health, and enhance outcomes in these potential liver transplant candidates. How to cite this article: Kumar M, Abbas Z, Gazder DP,

Indexed as

End-stage liver diseaseLiver transplant candidatesMicronutrient deficiency

Identifiers

PMID40718614
PMCPMC12288596

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.