Evidence map›Paper›PMID 40718547›Full record

ReviewOpen forum infectious diseases2025

Systematic Review and Expert Consensus on the Use of Long-acting Monoclonal Antibodies for Prevention of Respiratory Syncytial Virus Disease: ARMADA (Advancing RSV Management And Disease Awareness) Taskforce.

Paolo Manzoni, Eugenio Baraldi, Fabio Midulla, Olivier Claris, Sandro Dessardo, Terho Heikkinen, Richard Thwaites, Bosco Paes, Xavier Carbonell-Estrany, Dmytro Dobryanskyy and 15 more

Abstract readReview
In one paragraph

Review in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Paolo ManzoniDepartment of Public Health and Pediatric Sciences, University of Torino School of Medicine, Turin, Piedmont, Italy.ORCID https://orcid.org/0000-0003-1340-3493
Eugenio BaraldiDepartment of Women's and Children's Health, University Hospital of Padova, Veneto, Italy.ORCID https://orcid.org/0000-0002-1829-3652
Fabio MidullaDepartment of Pediatrics and Pediatric Neuropsychiatry, Sapienza University of Rome, Rome, Italy.
Olivier ClarisHospices Civils de Lyon, Hôpital de la Croix Rousse, Service de néonatologie et réanimation néonatale, Bron, France.
Sandro DessardoDepartment of Pediatrics, University Hospital Centre, Zagreb, Croatia.
Terho HeikkinenDepartment of Pediatrics, University of Turku and Turku University Hospital, Turku, Finland.ORCID https://orcid.org/0000-0001-6504-0116
Richard ThwaitesThe Neonatal Unit, Royal Stoke University Hospitals, Stoke-on-Trent, UK.ORCID https://orcid.org/0000-0001-5338-8537
Bosco PaesDepartment of Pediatrics (Neonatal Division), McMaster University and McMaster Children's Hospital, Hamilton, Ontario, Canada.
Xavier Carbonell-EstranyNeonatology Service, Hospital Clinic, Barcelona, Spain.
Dmytro DobryanskyyDepartment of Pediatrics, Lviv National Medical University, Lviv, Ukraine.ORCID https://orcid.org/0000-0002-4114-8701
Merih CetinkayaDepartment of Neonatology, Health Sciences University, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Adel S Al HarbiDepartment of Pediatrics, Prince Sultan Military Medical City, Alfaisal University, Riyadh, Saudi Arabia.
Ji-Man KangDepartment of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, South Korea.
Anne Goh Eng NeoDepartment of Pediatrics, KK Women's and Children's Hospital, Singapore.
Hsin ChiDepartment of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.
Guilherme Sant'AnnaDepartment of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0003-1633-3654
Mónica Villa GuillénDepartment of Medical Management, National Institute of Health Children´s Hospital of Mexico Federico Gómez, Mexico City, Mexico.
Gonzalo Luis MarianiDivision of Neonatology, Departments of Pediatrics, Instituto Universitario Hospital Italiano, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-4151-6751
Marco Aurelio Palazzi SafadiDepartment of Pediatrics, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
Soledad UrzuaDepartment of Neonatology, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Heather J ZarDepartment of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.
Pierre GoussardDepartment of Paediatrics and Child Heath, Stellenbosch University, Stellenbosch, South Africa.ORCID https://orcid.org/0000-0003-1146-1307
Barry Rodgers-GrayViolicom Medical Limited, Aldermaston, UK.ORCID https://orcid.org/0000-0003-0954-5587
Nicola WaghorneViolicom Medical Limited, Aldermaston, UK.
Manuel Sanchez LunaNeonatology Division, University General Hospital Gregorio Maranon, Complutense University of Madrid, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long-acting monoclonal antibodies (LAmAbs) could dramatically reduce the respiratory syncytial virus (RSV) disease burden in children if implemented using clear, evidence-based recommendations. Methods: The ARMADA Taskforce-an international, multidisciplinary expert panel-undertook a systematic review to develop LAmAbs consensus recommendations for RSV disease prevention in children. Results: The Taskforce recommends LAmAbs for all infants aged <8 months in the absence of maternal RSV vaccination, preterm infants (<37 weeks' gestational age) aged <12 months, and children <24 months with high-risk conditions. Seasonal LAmAb administration is recommended, although in RSV-endemic countries decisions should be made locally concerning administration year-round or with peak RSV incidences. Conclusions: The Taskforce strongly endorses LAmAbs implementation based on their efficacy, effectiveness, and public health impact. These recommendations provide a blueprint to inform guidelines worldwide. Wider equitable access to LAmAbs at affordable prices, especially in low- and middle-income countries is needed to reduce the childhood RSV burden.

Indexed as

disease preventionlong-acting monoclonal antibodies (LAmAbs)public health impactrespiratory syncytial virus (RSV)

Identifiers

PMID40718547
PMCPMC12290402

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.