Evidence map›Paper›PMID 40718517›Full record

ArticleAEM education and training2025

Epinephrine Dosing by Emergency Medicine Residents During a Simulated Prehospital Pediatric Cardiac Arrest.

Henry J Higby, John D Hoyle, Joshua D Mastenbrook, Philip A Pazderka, Sarah Fichuk, Austin Wilkinson, Caleb Porter

Abstract read
In one paragraph

Article in AEM education and training, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Henry J HigbyDepartment of Emergency Medicine Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.ORCID https://orcid.org/0009-0004-0136-6159
John D HoyleSimulation Center and Departments of Emergency Medicine & Pediatrics Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.ORCID https://orcid.org/0000-0003-4948-2533
Joshua D MastenbrookDepartment of Emergency Medicine Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.ORCID https://orcid.org/0000-0002-9928-3674
Philip A PazderkaDepartment of Emergency Medicine Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.
Sarah FichukDepartment of Emergency Medicine Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.
Austin WilkinsonSimulation Center Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.
Caleb PorterSimulation Center Western Michigan University Homer Stryker MD School of Medicine Kalamazoo Michigan USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric prehospital dosing errors occur at high rates, up to 60% for epinephrine. Senior emergency medicine residents (EMR) in the Western Michigan University Homer Stryker MD School of Medicine (WMed) residency respond as EMS physicians to cardiac arrests in Kalamazoo County. We sought to determine error rates for weight estimation, epinephrine doses, dose administration mechanics, and esophageal intubation (EI) recognition by EMRs at the end of the PGY-1 year, during EMS physician training summative testing. Methods: Sixteen PGY-1 EMRs were observed during a simulation: 5-year-old with an EMS EI in asystole requiring multiple epinephrine administrations by the EMR. All EMRs had completed Pediatric Advanced Life Support (PALS). Two observers scored performance. Scenarios were recorded. Recordings and scores were reviewed and discussed by observers. Any disagreements were resolved by consensus. Dosing error was defined as > 20% difference from the correct dose. Results: All EMRs obtained correct weight with 15 (94%; 72.0%, 99.0%) using length-based tape (LBT) and one (6%) guessing. Four near-miss errors occurred with the LBT. Four (25%) and two (12.5%) of the first and second epinephrine doses, respectively, were incorrect. Five (50%) errors occurred using graduations on the preloaded syringe, and five (50%) were due to air bubbles in the administration syringe. There were no ten-fold errors. Three (19%) EMRs took 3 attempts to assemble the preloaded syringe, six (38%) did not screw the preloaded syringe together correctly, seven (44%) had difficulty attaching a stopcock to the preloaded syringe, and 14 (88%) did not prime the stopcock. One (6%) failed to recognize EI. Conclusions: PALS-certified PGY-1 EMRs, accurately estimated patient weight, had a high rate of epinephrine dosing errors and frequent difficulty assembling preloaded syringes. To address these errors, training will be developed that includes a checklist, LBT use, weight determination hierarchy, assembling epinephrine preloaded syringes, techniques for appropriate dose administration, and recognition of EI.

Identifiers

PMID40718517
PMCPMC12286758

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.