Evidence map›Paper›PMID 40718470›Full record

ReviewInternational journal of food science2025

Biobased Organic Nanoparticles: A Promising Versatile Green Tool for Novel Antimicrobial Agents for Improved Safety.

Edith Dube, Grace Emily Okuthe

Abstract readReview
In one paragraph

Review in International journal of food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. A WR3-NHMaterials today. Bio · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Edith DubeDepartment of Biological & Environmental Sciences, Walter Sisulu University, Mthatha, South Africa.ORCID https://orcid.org/0000-0003-0371-9259
Grace Emily OkutheDepartment of Biological & Environmental Sciences, Walter Sisulu University, Mthatha, South Africa.ORCID https://orcid.org/0000-0001-6357-6742

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biobased organic nanoparticles possess nanoscale size, large surface area, tunable surface charge, and strong functionalization capacity, significantly enhancing their antimicrobial performance. Derived from renewable materials such as polysaccharides, proteins, and plant-based compounds, they provide a sustainable and ecofriendly alternative to synthetic antimicrobial agents. Their antimicrobial effects include disrupting microbial membranes, generating reactive oxygen species, and interfering with essential cellular processes, making them effective even against drug-resistant pathogens. Additionally, when used as drug delivery systems, they improve therapeutic outcomes by enhancing compound stability, bioavailability, and targeted delivery while minimizing toxicity. This review comprehensively analyses their structural features, mechanisms of action, and dual roles in infection control and drug delivery. It also addresses key challenges, including nanoparticle stability, scalability, and biosafety. The review concludes with future directions, emphasizing the need to optimize nanoparticle design, understand their interactions with microbial cells, and develop safe, cost-effective, and environmentally friendly synthesis methods to support their broader application in sustainable healthcare.

Indexed as

cellular uptakeencapsulationnanoparticlenaturally derivedpathogen

Identifiers

PMID40718470
PMCPMC12297162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.