Evidence map›Paper›PMID 40718394›Full record

ArticleNeuro-oncology advances2025

Beyond the sella: Expanded endoscopic endonasal approaches for pituitary tumors.

Erion Junior de Andrade, Saira Alli, Raj Sindwani, Varun R Kshettry, Pablo F Recinos

Abstract read
In one paragraph

Article in Neuro-oncology advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erion Junior de AndradeDepartment of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Saira AlliDepartment of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Raj SindwaniDepartment of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Varun R KshettryDepartment of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.
Pablo F RecinosDepartment of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, USA.ORCID https://orcid.org/0000-0002-9748-2784

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expanded endoscopic endonasal approaches (EEAs) have significantly advanced the surgical management of invasive pituitary tumors that extend beyond the sella turcica. They are particularly important in functioning tumors to achieve biochemical remission. In this article, we review the classification and application of expanded EEAs in addressing tumors invading the anterior skull base, suprasellar cisterns, clivus, and cavernous sinus. The anatomical basis, techniques, and indications for the endoscopic endonasal transtuberculum-transplanum, transclival, and transcavernous approaches, as well as the resection of the medial wall of the cavernous sinus, are discussed. The outcomes of these approaches are reviewed and our surgical strategy for these tumors is presented. Despite advances in technology and our understanding of the parasellar anatomy, we emphasize the importance of a multidisciplinary team and graded experiential learning for surgeons to minimize the complication rates associated with these technically advanced approaches.

Identifiers

PMID40718394
PMCPMC12288133

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.