Evidence map›Paper›PMID 40718368›Full record

ArticleInfection and drug resistance2025

HIV Complicated with Talaromyces Marneffei Multisystem Infection: A Case Report and Literature Review.

Guomin Zhang, Guangrong Wu, Yuanyuan Xu, Li Yang, Wei Yang

Abstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Case Report:Frontiers in pediatrics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guomin ZhangDepartment of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, People's Republic of China.
Guangrong WuDepartment of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, People's Republic of China.ORCID 0009-0002-9399-6304
Yuanyuan XuDepartment of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, People's Republic of China.ORCID 0009-0002-6076-2640
Li YangDepartment of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, People's Republic of China.
Wei YangDepartment of Radiology, The Third Affiliated Hospital of Zunyi Medical University (The First People's Hospital of Zunyi), Zunyi, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

HIV-infected individuals typically present with diverse clinical manifestations and heightened susceptibility to various opportunistic infections. We present a case of a hospitalized HIV patient presenting with dizziness, headache, and lip numbness. Neuroimaging revealed disseminated lesions involving bilateral cerebral hemispheres, spinal cord, pulmonary parenchyma, and mesenteric lymph nodes, subsequently confirmed through cerebrospinal fluid analysis and genetic testing as systemic TM infection. Following a 10-day course of intravenous amphotericin B, the patient demonstrated symptomatic improvement and was discharged. Post-discharge management included combination antiretroviral therapy (Bictegravir/Emtricitabine/Tenofovir alafenamide) with oral itraconazole prophylaxis. One-year follow-up imaging demonstrated near-complete resolution of systemic lesions. This report highlights characteristic radiological patterns and emphasizes the importance of considering disseminated TM infection in HIV patients with neurological involvement, particularly in endemic regions.

Indexed as

case reportCTHIVMRImultisystem infectiontalaromyces marneffei

Identifiers

PMID40718368
PMCPMC12292354

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.