ReviewFrontiers in global women's health2025
Vitamin K and women's health: a review.
Review in Frontiers in global women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Vitamin K in brain metabolism and cognitive function: mechanistic evidence, human associations, and unresolved questions.Metabolic brain disease · 2026Review
- Vitamin K as an Endocrine Modulator: Mechanistic Links to Glucose Metabolism and Beyond.Nutrients · 2026Review
- Review
- Micronutrient balance and brain function: neuropsychological, metabolic, and clinical interactions.Frontiers in molecular biosciences · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vitamin K is a fat-soluble vitamin essential in various physiological functions such as blood coagulation, bone metabolism, cardiovascular health, glucose regulation, immune function, neuroprotection, and vascular health. In this narrative review, studies from databases including PubMed, Google Scholar, Scopus, and the institutional database of Zayed University were selected. The role of vitamin K in women's health, with a focus on osteoporosis, postmenopausal health, cardiovascular health, diabetes, cancer, kidney health, brain health, vascular health, and pregnancy were explored. The role of vitamin K in activating vitamin K-dependent proteins is essential for many of its functions. Vitamin K-dependent proteins such as osteocalcin and matrix gla protein are crucial to many physiological processes such as bone mineralization, vascular calcification, and cardiovascular health. It also modulates glucose metabolism by enhancing insulin sensitivity, reducing oxidative stress, and influencing β-cell function. Vitamin K exhibits anti-cancer properties in cancer research, particularly in breast, cervical, and ovarian cancer models. It also plays a role in brain health including cognitive function, neuroinflammation reduction, and neurodegenerative disease prevention. Similarly in kidney diseases, vitamin K has been linked to chronic kidney disease progression and vascular calcification. Vitamin K's role in pregnancy includes its impact on neonatal coagulation and neurodevelopmental outcomes. Despite the promising role of vitamin K, findings are mixed on its role in bone mineral density and fracture prevention, cardiovascular protection, protection against vascular calcification, diabetes prevention, cancer risk, kidney dysfunction, and its role in maternal and child health. These highlight the need for further research, particularly longitudinal and randomized controlled trials, to determine optimal intake, efficacy of supplementation, and long-term health impacts of vitamin K in women.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.