Evidence map›Paper›PMID 40718291›Full record

ArticleCureus2025

Infertility as a Rare Manifestation of Pituitary Involvement in Granulomatosis With Polyangiitis: A Case Report.

Mohammad Syedul Islam, Quazi Mamtaz Uddin Ahmed, Farzana Ahmed, Md Ashraf Uddin, Naznin Naher

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad Syedul IslamDepartment of Internal Medicine, Bangladesh Medical University, Dhaka, BGD.
Quazi Mamtaz Uddin AhmedDepartment of Internal Medicine, Bangladesh Medical University, Dhaka, BGD.
Farzana AhmedDepartment of Paediatrics, Marks Medical College and Hospital, Dhaka, BGD.
Md Ashraf UddinDepartment of Internal Medicine, Bangladesh Medical University, Dhaka, BGD.
Naznin NaherDepartment of Internal Medicine, Bangladesh Medical University, Dhaka, BGD.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Granulomatosis with polyangiitis is a rare autoimmune disease that affects small-sized blood vessels. It most commonly involves the lungs, kidneys, and the areas around the nose and throat, but can also affect other organs, including the nervous system. Enlargement of the pituitary gland may cause a mass effect, and pituitary dysfunction can occur. Among pituitary hormone abnormalities, hypogonadotropic hypogonadism is more common than other hormonal deficiencies. Pituitary involvement may arise at any stage of the disease, sometimes even as the initial presentation. We report a rare case of granulomatosis with polyangiitis with pituitary dysfunction presenting as infertility, along with pulmonary and systemic manifestations.

Indexed as

anca associated vasculitiscyclophosphamide therapyhypogonadotropic hypogonadisminfertilitypituitary dysfunction

Identifiers

PMID40718291
PMCPMC12296856

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.