ArticleCureus2025
Ultrasound-Guided Synovial Biopsy in Undifferentiated Monoarthritis: A Case Series From Bangladesh.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Ultrasound-guided synovial biopsy (USG-SB) is a minimally invasive technique useful in diagnosing joint tuberculosis, particularly when conventional methods fail. However, its role in diagnosing tubercular arthritis in Bangladesh remains underexplored. This study presents a case series of five patients with monoarthritis - three with ankle involvement and two with knee joint tuberculosis - evaluated using USG-SB or aspiration. The procedures were performed using a high-resolution musculoskeletal ultrasound (14-6 MHz probe, Mindray, Shenzhen, China). Synovial tissue samples were analyzed via histopathology and GeneXpert (Cepheid, Sunnyvale, California, US) testing, while synovial fluid was examined via cytology, acid-fast bacilli (AFB) staining, and GeneXpert. Tuberculosis was confirmed histologically in three cases, GeneXpert was positive in two, and AFB staining was positive in one. These findings support USG-SB as a safe, effective, and minimally invasive diagnostic option for tubercular arthritis, particularly in resource-limited settings like Bangladesh.
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