ArticleThe World Allergy Organization journal2025
Risk behaviours and non-atopic comorbidities of adolescents with asthma.
Article in The World Allergy Organization journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Risk behaviours, obesity, and neuropsychiatric comorbidity have been demonstrated in various chronic diseases but are less well described among adolescents with asthma. Methods: We clinically assessed asthma status at the 18-year follow-up visit of the Danish Copenhagen Prospective Studies on Asthma in Childhood (COPSAC Results: A total of 370 individuals (90%) completed the 18-year visit, and 93 of these (25.1%) had current asthma. Comparing adolescents with and without asthma, binge drinking was reported in 75.2% vs 66.0%, current smoking in 26.9% vs 32.9%, and drug use in 16.1% vs 26.0%. High daily screen use was reported in 25.8% vs 16.6%; 26.9% vs 17.3% reported self-destructive behaviour; 24.7% vs 14.1% had neuropsychiatric comorbidity, and 10.8% vs 6.9% had obesity. In univariate analyses, asthma was associated with self-destructive behaviour, OR = 1.84 (1.03-3.21), p = 0.035, and neuropsychiatric comorbidity, OR = 2.01 (1.11-3.56), p = 0.019. In multivariable analysis with backward selection, asthma was associated with neuropsychiatric comorbidity, OR = 2.04 (1.004-4.12), p = 0.049, a trend of increased self-destructive behaviour, OR = 1.76 (0.93-3.29), p = 0.079, and less drug use, OR = 0.59 (0.29-0.96), p = 0.045. Conclusion: Asthma was associated with neuropsychiatric comorbidity and self-destructive behaviour, but less drug use. There were no consistent associations with other risk behaviours or obesity.
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