Evidence map›Paper›PMID 40718119›Full record

ArticleAsia Pacific allergy2025

Serum neuropilin-1 level may predict airway remodeling based on age and smoking status in asthma.

Ji-Yoon Oh, Chae Eun Lee, Seo Young Kim, Hyunkyoung Kim, Yu Ri Kang, Ji-Hyang Lee, Woo-Jung Song, Hyouk-Soo Kwon, You Sook Cho, Tae-Bum Kim

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Article in Asia Pacific allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ji-Yoon OhDivision of Allergy, Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-2339-7878
Chae Eun LeeDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Seo Young KimDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Hyunkyoung KimDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yu Ri KangDivision of Allergy and Respiratory Medicine, Department of Internal medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
Ji-Hyang LeeDepartment of Allergy and Clinical Immunology, Seoul National University Hospital, Seoul, Korea.
Woo-Jung SongDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Hyouk-Soo KwonDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
You Sook ChoDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Tae-Bum KimDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Airway remodeling in asthma is induced by the production of vascular endothelial growth factor, and this process is mediated by neuropilin-1 (NRP-1). Objective: To investigate the association between the serum level of NRP-1 and clinical characteristics in asthma. Methods: We measured the serum level of NRP-1 and performed subgroup analysis of NRP-1 according to the clinical characteristics of 421 asthma patients registered in the Cohort for Reality and Evolution of Adult Asthma in Korea. Results: The serum level of NRP-1 was significantly higher in the group under 65 years of age than in the group over 65 years of age (1628.36 ± 589.51 vs 1416.75 ± 671.42; Conclusion: Serum NRP-1 level was high in asthma patients with a younger age and smoking history, suggesting its potential as a clinical marker for predicting early-stage airway remodeling based on the age and smoking status.

Indexed as

Airway remodelingasthmaneuropilin-1

Identifiers

PMID40718119
PMCPMC12289087

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.