Evidence map›Paper›PMID 40718092›Full record

ArticleSexual medicine2025

The effect of a single functional neurology session on thermography of the genital region and sexual function in patients with premature ejaculation.

Vicente Javier Clemente-Suárez, Jorge Rey-Mota, Guillermo Escribano-Colmena, Noelia Vanessa Marín, Jesús Fernandez-Lucas

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Article in Sexual medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Vicente Javier Clemente-SuárezFaculty of Medicine, Health and Sports, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.ORCID https://orcid.org/0000-0002-2397-2801
Jorge Rey-MotaFaculty of Medicine, Health and Sports, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.
Guillermo Escribano-ColmenaFaculty of Medicine, Health and Sports, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.
Noelia Vanessa MarínFaculty of Medicine, Health and Sports, Universidad Europea de Madrid, Villaviciosa de Odón, 28670 Madrid, Spain.
Jesús Fernandez-LucasApplied Biotechnology Group, Universidad Europea de Madrid, Urbanización El Bosque, 28670 Villaviciosa de Odón, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Premature ejaculation (PE) is a common male sexual dysfunction with limited long-term therapeutic options. Pharmacological and behavioral treatments often yield only temporary improvement, and alternative neuromodulatory strategies remain underexplored. Functional neurology, which targets autonomic and sensory-motor regulation, may offer a novel approach. Aim: To evaluate the effect of a single functional neurology intervention on genital thermoregulation and ejaculatory latency in men with PE. Methods: Fifty-two men diagnosed with PE participated in a pre-post intervention study. Each underwent a single session of functional neurology aimed at modulating nociceptor and mechanoreceptor pathways. Genital thermoregulation was assessed using infrared thermography, and ejaculatory function was measured via intravaginal ejaculatory latency time (IELT) and self-report at baseline, after the first post-treatment sexual encounter, and at 1-month follow-up. Statistical analyses included repeated-measures ANOVA, paired Outcomes: Significant improvements in IELT and genital temperature were expected following the intervention, supporting its role in enhancing autonomic regulation and microvascular circulation. Results: Intravaginal ejaculatory latency time increased significantly from a baseline of 20.4 ± 11.5 seconds to 439.2 ± 214.5 seconds post-treatment, with sustained effects at 1 month (498.0 ± 171.6 seconds; Clinical Implications: Functional neurology may be a non-invasive, fast-acting intervention for improving ejaculatory control in PE by promoting autonomic balance and vascular function. Thermography proved useful as a biomarker for physiological changes and treatment efficacy. Strengths and Limitations: This study is the first to evaluate thermographic and ejaculatory outcomes after a functional neurology intervention in PE. Strengths include objective and subjective measures, while limitations involve the lack of a control group, small sample size, and short-term follow-up. These results should be confirmed through randomized controlled trials. Conclusion: A single session of functional neurology significantly improved both genital thermoregulation and ejaculatory latency in men with PE. These findings support the integration of neuromodulatory techniques into multidisciplinary strategies for sexual dysfunction treatment.

Indexed as

autonomic nervous systemejaculation; prematurefunctional neurologygenital blood flowintravaginal ejaculatory latency timepremature ejaculationthermographyvascular regulation

Identifiers

PMID40718092
PMCPMC12296338

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