Evidence map›Paper›PMID 40718057›Full record

ReviewSAGE open medicine2025

Interplay of rheumatoid arthritis and cardiovascular disease: Insights and prospects.

Anastasia V Poznyak, Nikolay A Orekhov, Alexey V Churov, Irina Alexandrovna Starodubtseva, Dmitry Felixovich Beloyartsev, Tatiana Ivanovna Kovyanova, Vasily N Sukhorukov, Alexander N Orekhov

Abstract readReview
In one paragraph

Review in SAGE open medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Women's cardiovascular health in 2025:Saudi medical journal · 2026
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anastasia V PoznyakInstitute for Atherosclerosis Research, Moscow, Russia.ORCID https://orcid.org/0000-0002-1516-1320
Nikolay A OrekhovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Alexey V ChurovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Irina Alexandrovna StarodubtsevaDepartment of Polyclinic Therapy, NN Burdenko Voronezh State Medical University, Voronezh, Russia.
Dmitry Felixovich BeloyartsevVascular Surgery Department, A. V. Vishnevsky National Medical Research Center of Surgery, Moscow, Russia.
Tatiana Ivanovna KovyanovaInstitute for Atherosclerosis Research, Moscow, Russia.
Vasily N SukhorukovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.
Alexander N OrekhovLaboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia.ORCID https://orcid.org/0000-0002-6495-1628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis significantly increases the risk of cardiovascular disease due to chronic inflammation. This review's purpose is to critically analyze the intricate relationship between rheumatoid arthritis and cardiovascular disease, highlighting the mechanisms by which systemic inflammation contributes to cardiovascular risk and the effectiveness of current treatment strategies. We systematically evaluate existing literature on conventional cardiovascular risk factors in rheumatoid arthritis patients, as well as inflammation-specific markers that influence cardiovascular outcomes. Our conclusions indicate that while several treatment modalities, including methotrexate and other disease-modifying agents, may mitigate cardiovascular risk, there is a prevalent underestimation of true risk by standard cardiovascular disease assessment protocols. This review provides unique contributions by emphasizing the importance of integrating novel risk factors into assessment protocols and advocating for personalized management strategies that cater to the specific needs of rheumatoid arthritis patients. By synthesizing these elements, we aim to enhance understanding and guide clinicians in improving outcomes for rheumatoid arthritis patients at heightened risk of cardiovascular complications.

Indexed as

Cardiovascularrheumatology/clinical immunology

Identifiers

PMID40718057
PMCPMC12290359

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.