SynthesisFrontiers in dental medicine2025
The histological and radiological evaluation of autologous peripheral venous blood concentrates in socket preservation: a systematic review and meta-analysis.
Synthesis in Frontiers in dental medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Objectives: A detailed meta-analysis and systematic search was conducted to assess the histologic and radiographic efficacy of autologous peripheral venous blood concentrates (APVBCs) for the socket preservation. Design: Electronic databases were searched until 31 January 2025. Randomized controlled trials (RCTs) and controlled clinical trials (CCTs) in English were identified. Alveolar bone reconstruction was assessed through histologic and radiographic evaluation after tooth extraction. Data were analyzed using Revman5.3, and the risk of bias was evaluated with the Cochrane Collaboration tool. Results: A total of 16 studies (12 RCTs and 4 CCTs) involving 619 sites was included in our meta-analysis. The results indicated that the APVBCs application significantly reduced the vertical bone resorption in the buccal ridge (standardized mean difference [SMD]: -0.30; 95% confidence interval [CI]: -0.54 to -0.06; Conclusions: APVBCs in socket preservation can reduce vertical bone resorption and enhance new bone formation. Meanwhile, APVBCs may improve osteogenic efficiency with bone graft material. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420250653020, identifier CRD420250653020.
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