ArticleFrontiers in pharmacology2025
Osteoporosis diagnosis and ingredients of prescription medications: a population-based study.
Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Osteoporosis (OP) is common in the elderly, who typically have multiple comorbidities. Current guidelines for managing drug-induced OP are limited due to the complexity of multi-agent medications and the lack of sufficient clinical data. Methods: Information of demographics, health status, prescription medication use, OP diagnoses, and bone fracture history in US adults aged ≥50 years was from NHANES. Administration of individual medication ingredients was extracted and association between medication component use and OP diagnosis was determined. National trends in OP diagnosis, prescription medication use, and medication ingredient administrations were examined. Results: OP diagnosis prevalence rose from 9.00% to 13.23% during 1999-March 2020 (p-trend = 0.00). Increased medication prescription was noted in OP patients (p-trend Conclusion: The findings of this study contribute to updating and improving the existing guidelines. Efforts are recommended to examine how the use of medications contribute to OP and to identify alternative treatments for comorbidities.
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