Evidence map›Paper›PMID 40717972›Full record

ReviewFrontiers in pharmacology2025

Application of cell-derived vesicle-based biomimetic drug delivery system in tumor therapy.

Yan Mei, Maochang Liu, Meng Mei

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yan Mei *Department of Pharmacy, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Maochang Liu *Department of Pharmacy, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Meng MeiDepartment of Pharmacy, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-derived vesicles play a crucial role in intercellular information transmission and serve as vital carriers facilitating cell-to-cell communication. These vesicles contain specific biological information from their parental cells, enabling them to transport proteins, cytokines, mRNA, and DNA to other cells or organs. Presently, cell-derived vesicles have extensive application in inhibiting tumor growth and metastasis, as well as in tumor diagnosis and early screening. Numerous studies have highlighted the potential of cell-derived vesicles as drug delivery systems, showcasing advantages such as enhanced biocompatibility, natural active targeting, improved systemic circulation, and greater efficacy compared to conventional drug delivery carriers. In this article, we aim to explore the utilization of cell-derived vesicles as drug delivery systems in tumor therapy, focusing on various drug-loading techniques and analyzing the advantages and characteristics of different types of cell-derived vesicles. Our findings will provide valuable assistance in the development of drug delivery systems based on these vesicles.

Indexed as

biomimicrycell-derived vesiclesdrug deliveryhybrid nanovesiclestumor therapy

Identifiers

PMID40717972
PMCPMC12290409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.