ArticleFrontiers in veterinary science2025
Effect of transport stress on apoptosis and autophagy in goat lung cells.
Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Road transportation exposes goats to thermal, mechanical, and microbial stressors that can compromise their welfare by triggering pulmonary apoptosis and autophagy processes associated with tissue damage and immunosuppression. Methods: To explore potential biomarkers for transport-related welfare assessment, this study analyzed lung tissues from nine Ganxi goats ( Results: Results indicated time-dependent cellular stress patterns, where the 2 h group displayed elevated apoptosis rates, while the 6 h group exhibited upregulated Parkin expression ( Discussion: These findings highlight the need for further investigation into transport duration effects, with shorter intervals (e.g., ≤2 h) warranting evaluation for acute stress mitigation, and prolonged transport (e.g., >6 h) requiring characterization of cumulative autophagic impacts. The mechanistic insights can contribute to developing science-informed strategies for assessing transport stress, aligning animal welfare research with objectives to enhance sustainable livestock management practices.
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