ReviewCureus2025
Impact of Left Ventricular Assist Devices on the Quality of Life and Functional Outcomes in Advanced Heart Failure: A Comprehensive Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Guideline directed-medical therapy for heart failure within 3 months post LVAD implant and rehospitalization.JHLT open · 2026Article
- Depression and Suicidality in Patients with Left Ventricular Assist Devices and Advanced Cardiac Therapies: Mechanisms, Risk Factors, and Clinical Management.Medical sciences (Basel, Switzerland) · 2026Review
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Managing advanced heart failure (HF) remains a major clinical challenge, especially for patients who no longer respond to conventional treatment options, or are not candidates for heart transplantation. In such cases, left ventricular assist devices (LVADs) have become an important option, offering mechanical support that has the potential to extend life and improve daily functioning. With ongoing advancements in technology, there is growing interest in understanding how LVADs impact not just survival, but also patients' quality of life (QoL) and overall recovery. This narrative review explores the role of LVAD therapy in improving functional status and QoL in patients with advanced HF. It draws on clinical research from the past 15 years to examine physical, psychological, and social outcomes, as well as the challenges and complications associated with this treatment. A structured PubMed search was performed using predefined MeSH terms and keywords related to LVADs. After removing duplicates, 68 articles were identified. Eleven reviewers screened titles and abstracts, followed by full-text review and data extraction. Studies were included if they involved adults, were conducted in the past 15 years, and used clinical or observational study designs. Non-English, pediatric, and pregnancy-related studies were excluded. A total of 44 studies met the criteria. LVADs were associated with improvements in physical function, exercise capacity, and QoL. However, patients often faced psychological stress and medical complications. Better pre-implant health and strong support systems contributed to more favorable outcomes. LVADs offer meaningful improvements in both survival and QoL, but holistic, patient-centered care remains key to optimizing outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.