Evidence map›Paper›PMID 40717871›Full record

ArticleCureus2025

Synchronous Sinonasal Inverted Papilloma With Nasolacrimal Squamous Cell Carcinoma: An Uncommon Case Report of Malignant Transformation of Inverted Papilloma.

Julide Kasaboglu, Stoyan Dimitrov, Milena Mitkova, Spiridon Todorov, Tsvetomir Marinov

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julide KasabogluDepartment of Otolaryngology, Head and Neck Surgery, University Hospital Queen Joanna ISUL, Sofia, BGR.
Stoyan DimitrovDepartment of Otolaryngology, Head and Neck Surgery, Medical University-Sofia, Sofia, BGR.
Milena MitkovaDepartment of Otolaryngology, Head and Neck Surgery, Medical University-Sofia, Sofia, BGR.
Spiridon TodorovDepartment of Otolaryngology, Head and Neck Surgery, Medical University-Sofia, Sofia, BGR.
Tsvetomir MarinovDepartment of Anesthesiology and Reanimation, Medical University-Sofia, Sofia, BGR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nasolacrimal tumors are exceedingly rare head and neck pathologies. They are locally invasive and have an increased possibility of aggressive malignant transformation. These tumors are clinically presented with a palpable mass, obstruction of nasolacrimal drainage, epiphora, and nasal congestion. Nasolacrimal carcinomas are rare malignancies that often take a long time before the correct diagnosis is made. The combination of endoscopic and open en-bloc resection can provide complete removal of locally advanced nasolacrimal tumors. A multidisciplinary team, chemo-radiotherapy, and follow-up monitoring are essential for the effective management of such tumors. We report a case of a 41-year-old male patient with presentation of epiphora and a paranasal lump. Imaging showed an advanced nasolacrimal tumor with infiltration of surrounding structures. Pathologic examination demonstrated nasolacrimal keratinizing squamous cell carcinoma (SCC) associated with sinonasal inverted papilloma. A multidisciplinary approach, including radical surgery and chemo-radiotherapy, rendered success in achieving remission with a four-year disease-free follow-up.

Indexed as

inverted papillomalacrimal sacmalignancynasolacrimal duct systemsinonasalsquamous cell carcinoma

Identifiers

PMID40717871
PMCPMC12296299

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.