ArticleHeart rhythm O22025
Preprocedural neutrophil-to-lymphocyte ratio: A novel predictor of permanent pacemaker implantation in self-expandable vs balloon-expandable valve cohorts following transcatheter aortic valve implantation.
Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Preprocedural Biomarkers of Inflammation and Fibrosis and Echocardiographic Markers of Myocardial Remodeling in New-Onset Conduction Disorders After Transcatheter Aortic Valve Implantation.Medicina (Kaunas, Lithuania) · 2026Observational
- Preprocedural CALLY Index As a Novel Predictor of Pacemaker Requirement After Transcatheter Aortic Valve Replacement.CJC open · 2026Article
- De Ritis (AST/ALT) ratio as a predictor of early adverse outcomes following transcatheter aortic valve replacement.PloS one · 2026Article
- Prognostic value of the C-reactive protein-albumin-lymphocyte index for postoperative visual hallucinations following cardiac surgery.Frontiers in psychiatry · 2026Article
- Triglyceride-glucose index predicts early, short-term, and long-term mortality after transcatheter aortic valve replacement.American heart journal plus : cardiology research and practice · 2026Article
- The association of inflammatory response with speckled global strain in recovered patients with myocarditis.Annals of medicine and surgery (2012) · 2026Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Transcatheter aortic valve implantation (TAVI) is the preferred treatment for severe aortic stenosis. This study examines the neutrophil-lymphocyte ratio (NLR) as a predictor of permanent pacemaker implantation (PPI) outcomes, comparing self-expandable valves (SEVs) and balloon-expandable valves (BEVs). Objective: This study aims to evaluate the effectiveness of the NLR in predicting PPI outcomes in patients undergoing TAVI with SEVs and BEVs. Methods: This retrospective cohort study at Kaplan Medical Center analyzed 305 patients with severe symptomatic aortic stenosis referred for TAVI from January 2010 to December 2019. Data on baseline characteristics, laboratory results, and clinical outcomes were collected, including NLR and PPI rates. Two logistic regression models were developed to identify predictors of TAVI-PPI outcomes for SEV and BEV cohorts. Results: In the SEV cohort, 59 of 199 patients (29.6%) required PPI, compared with 15 of 106 patients (14.2%) in the BEV cohort. The receiver operating characteristic (ROC) curve for SEV showed an area under the curve (AUC) of 0.70, indicating predictive ability of the NLR for TAVI-PPI outcomes. The BEV cohort had a lower AUC of 0.40 ( Conclusion: The NLR significantly predicts permanent pacemaker implantation after TAVI, especially for SEVs, but less for BEVs.
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