Evidence map›Paper›PMID 40717854›Full record

ArticleHeart rhythm O22025

An alternative method for phrenic nerve monitoring during cryoballoon procedures.

Alessio Marinelli, Konstantinos Trachanas, Maurizio Corso, Davide Fasoli, Michele Canton, Alessandro Costa, Federico Cecchini, Stefano Bonapace, Alessandro Mantovani, Melania Bonocore and 3 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alessio MarinelliAOOR Villa Sofia-Cervello, Villa Sofia Cardiology Department, Palermo, Italy.
Konstantinos TrachanasIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Maurizio CorsoIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Davide FasoliIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Michele CantonIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Alessandro CostaIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Federico CecchiniIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Stefano BonapaceIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.
Alessandro MantovaniUniversity and Azienda Ospedaliera Universitaria Integrata of Verona, Department of Endocrinology, Diabetes and Metabolism, Verona, Italy.
Melania BonocoreAOOR Villa Sofia-Cervello, Villa Sofia Cardiology Department, Palermo, Italy.
Antonino MignanoAOOR Villa Sofia-Cervello, Villa Sofia Cardiology Department, Palermo, Italy.
Carlo CiceroneAOOR Villa Sofia-Cervello, Villa Sofia Cardiology Department, Palermo, Italy.
Giulio MolonIRCCS Sacro Cuore-Don Calabria, Department of Cardiology, Negrar di Valpolicella, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cryoballoon ablation is associated with a consistent risk of phrenic nerve (PN) damage. Abdominal palpation associated with other strategies such as the diaphragmatic compound motor action potential (CMAP) has been shown to be an effective and reliable method for preventing this complication. Objective: The purpose of this study was to evaluate the diagnostic performance of a new surface CMAP electrodes positioning. Methods: A total of 150 patients underwent cryoballoon ablation. During the procedure, we placed the CMAP leads per the manufacturer's instructions and our alternative method, named NeedMAP, by placing electrocardiographic electrodes on the anterior axillary line. We simultaneously recorded the CMAP and the NeedMAP. CMAP monitoring with a 35% decrease cutoff for the diagnosis of nerve threatening was considered the gold standard. The NeedMAP decrease threshold also was set at 35%. Results: A total of 438 cryoballoon applications were performed on the right pulmonary veins. Mean CMAP amplitude was 0.60 ± 0.33 mV compared to NeedMAP amplitude 0.85 ± 0.46 mV ( Conclusion: The NeedMAP signal for PN monitoring during cryoballoon ablation seems to be a reliable method, shows good sensitivity and specificity, and can help clinicians in preventing PN damage.

Indexed as

Atrial fibrillationAtrial fibrillation complicationsCompound motor action potentialCryoballoon ablationPhrenic nerve damage

Identifiers

PMID40717854
PMCPMC12287966

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.