Evidence map›Paper›PMID 40717772›Full record

ArticleFrontiers in pediatrics2025

Association between vitamin B

Guimei Du, Xinghui Li

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Guimei DuDepartment of Dermatology, The 906th Hospital of PLA, Ningbo, Zhejiang, China.
Xinghui LiDepartment of Dermatology, The Yancheng Clinical College of Xuzhou Medical University, The First People's Hospital of Yancheng, Yancheng, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: There are few studies investigating the relationship between vitamin B6 status and the odds of eczema in children and adolescents. Hereby, this study aims to explore the association between vitamin B6 status and eczema in children and adolescents. Methods: A cross-sectional study was conducted based on National Health and Nutrition Examination Surveys (NHANES) 2005-2006. The vitamin B6 status was assessed based on levels of 4-PA, PLP and vitamin B6 metabolic rate (4-PA/PLP) by high-performance liquid chromatography. The weighted univariate and multivariate logistics regression models were adopted to explore the association between vitamin B6 status with and the odds of eczema in children and adolescents, with odds ratio (ORs) and 95% confidence intervals (CIs). The subgroup analysis based on age, gender, atopy and body mass index (BMI) were further performed to explore whether the association between vitamin B6 status and eczema in children and adolescents remains robust. Results: A total of 2,256 eligible children and adolescents were included for further analysis, with the mean aged of 11.81 (±0.09) years old. Among them, 247 (10.95%) had eczema. After adjusted all covariates, we observed high 4-PA was associated with high odds of eczema (OR = 1.57, 95%CI: 1.01-2.44, Conclusion: Our study observed that high 4-PA and high vitamin B6 metabolic rate were associated with increased odds of eczema in children and adolescents. Maintaining high vitamin level may have potential benefits in reducing odds for eczema in children and adolescents.

Indexed as

4-pyridoxic acidchildhood eczemaNHANES databasevitamin B6vitamin B6, 5'-pyridoxal phosphate

Identifiers

PMID40717772
PMCPMC12289665

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