Evidence map›Paper›PMID 40717690›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Social determinants of dementia: A scoping review.

Sebastian Walsh, Matthias Klee, Esther K Hui, Usman Saeed, Sheena Waters, Isla Kuhn, Joyce Siette, Vasiliki Orgeta, Jean Stafford, Laura J Smith and 11 more

Abstract readScoping Review
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Multimorbidity, Polypharmacy, and Neighborhood Disadvantage as Determinants of Cognitive Performance in the ARCHES Cohort.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  2. From mapping evidence to engaging voices: Paving the way for research on the social determinants of dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
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  5. NADAlzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  17. Tackling social determinants of dementia will require qualitative research with the public and professionals.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  18. Social determinants of dementia: A scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Sebastian WalshCambridge Public Health, University of Cambridge, Forvie Site, Cambridge, UK.ORCID 0000-0001-8894-5006
Matthias KleeDepartment of General Internal Medicine and Psychosomatics, University Medical Centre Heidelberg, Heidelberg, Germany.
Esther K HuiDivision of Psychiatry, University College London, London, UK.
Usman SaeedInstitute of Medical Science, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Sheena WatersCentre for Preventive Neurology, Queen Mary University of London, London, UK.
Isla KuhnCambridge Public Health, University of Cambridge, Forvie Site, Cambridge, UK.
Joyce SietteThe MARCS Institute for Brain, Behaviour and Development, Western Sydney University, Westmead, NSW, Australia.
Vasiliki OrgetaDivision of Psychiatry, University College London, London, UK.
Jean StaffordAdvanced Care Research Centre, University of Edinburgh, Edinburgh, UK.
Laura J SmithCentre for Preventive Neurology, Queen Mary University of London, London, UK.
Stefano TamburinDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Daria E A JensenClinic of Cognitive Neurology, University Medical Center Leipzig, Leipzig, Germany.
Elisa MantovaniDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Avinash ChandraCentre for Preventive Neurology, Queen Mary University of London, London, UK.
Sarah-Naomi JamesInstitute of Cardiovascular Science, University College London, London, UK.
Eugene Y H TangPopulation Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.
David J LlewellynDepartment of Health and Community Sciences, University of Exeter Medical School, St Luke's Campus, Exeter, UK.
Isabelle F FooteInstitute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA.
Scott T ChiesaInstitute of Cardiovascular Science, University College London, London, UK.
Anouk F J GeraetsDepartment of Social Sciences, University of Luxembourg, Esch-sur-Alzette, Luxembourg.
DEMON SDOH International Research Group

Funding

Large-Scale Genomic Analysis of Aging-Related Cognitive Change Prior to Dementia OnsetR01AG073593 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI TUCKER-DROB, ELLIOT MAX · 2024 to 2025
$1.3M
NIA NIH HHS R01 AG073593the European Union's Horizon 2020 research and innovation program 803239the National Institute on Aging R01AG073593
6 · The paper itself

Abstract

Dementia risk is influenced by the social conditions in which people live. These social determinants of dementia (SDOD) are potential targets for prevention. We conducted a comprehensive scoping review to identify current evidence on SDOD in two stages: (1) review of systematic reviews on SDOD; and (2) review of primary literature to address identified gaps in the evidence base. Of the 3445 articles screened, 26 reviews and 74 primary studies were included. Evidence from reviews provide clear and consistent patterns for some SDOD (e.g., education, air pollution, socioeconomic status, ethnicity), while evidence for others is still emerging (e.g., housing quality/stability), or lacking entirely (e.g., incarceration). SDOD are important over the life course. Additional evidence is needed for understudied domains and to unravel the complex interactions between determinants, whilst education and air pollution stand out as key targets for public health interventions. HIGHLIGHTS: There is clear and consistent evidence for some social determinants of dementia (SDOD) across diverse domains. Evidence for other SDOD (e.g., housing, incarceration) is still emerging or lacking. Evidence for SDOD comes mainly from high-income countries. The complex intercorrelations between SDODs demand a nuanced analytical approach. Standardized measures and longer follow-up to study SDOD are recommended.

Indexed as

DementiaSocial Determinants of HealthHumansRisk FactorsSocioeconomic Factorsdementiaemploymentethnicityfood environmentgeographyhousingincomeinequalitiesphysical environmentpollutionpovertyreviewsocial determinantssocial inclusionsocioeconomic status

Identifiers

PMID40717690
PMCPMC12301702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.