ArticleJournal of Alzheimer's disease : JAD2025
Person-specific digital measurements of air pollutant exposure and biomarkers of Alzheimer's disease: Findings from a pilot study.
Article in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- The myth of digital biomarkers in Alzheimer's disease: how to make them a reality.Current opinion in psychiatry · 2026Review
- BSO-AD: An Ontology for Representing and Harmonizing Behavioral Social Knowledge in ADRD.medRxiv : the preprint server for health sciences · 2026Article
- Wearable Sensor Technologies and Gait Analysis for Early Detection of Dementia: Trends and Future Directions.Sensors (Basel, Switzerland) · 2025Review
- Volatile Organic Compounds (VOCs) in Neurodegenerative Diseases (NDDs): Diagnostic Potential and Analytical Approaches.Molecules (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
BackgroundAir pollution has been almost exclusively measured by region-level ambient exposure of particulate matter (PM) from government agencies (e.g., EPA), which does not capture the potentially large within-region variation and takes no consideration of human mobility in daily life. The use of region-level PM may have systematically biased the estimated associations with Alzheimer disease (AD).ObjectiveTo obtain pilot data on person-specific digital measurements of exposure to PM and volatile organic compounds (VOC) and to correlate them with AD biomarkers, including plasma and cerebrospinal fluid (CSF) analytes and amyloid and tau positron emission tomography (PET) signal, and to generate hypotheses about these correlations.MethodsFifty nine older participants underwent a 7-day digital collection of exposure to PM and VOC by Atmotube Pro, a validated wearable air quality sensor. Person-specific levels of PM and VOC were correlated with AD biomarkers. Sample sizes for future studies to detect the observed correlations were estimated.ResultsThe first functional principal components (FFPC) of 7-day exposure to PM and VOC captured 75% to 86% of the total variation. The FFPC of PM
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