Evidence map›Paper›PMID 40717109›Full record

ArticleImplementation science : IS2025

Translational framework for implementation evaluation and research: implementation strategies derived from normalization process theory.

Carl R May, Alyson Hillis, Bianca Albers, Laura Desveaux, Anthony Gilbert, Melissa Girling, Roman Kislov, Anne MacFarlane, Frances S Mair, Sebastian Potthoff and 2 more

Abstract read
In one paragraph

Article in Implementation science : IS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Carl R May *Department of Health Services Research and Policy, London, School of Hygiene and Tropical Medicine, 15-17 Tavistock Place, London, WC1H 9SH, UK. carl.may@lshtm.ac.uk.ORCID 0000-0002-0451-2690
Alyson Hillis *Department of Health Services Research and Policy, London, School of Hygiene and Tropical Medicine, London, UK.
Bianca AlbersInstitute for Implementation Science in Health Care, University of Zurich, Zurich, Switzerland.
Laura DesveauxLearning Health System Program Institute for Better Health, Trillium Health Partners, Toronto, Canada.
Anthony GilbertRoyal National Orthopaedic Hospital, Stanmore, Middlesex, UK.
Melissa GirlingDepartment of Nursing, Midwifery & Health, Northumbria University, Coach Lane Campus, Newcastle-Upon-Tyne, UK.
Roman KislovManchester Metropolitan University, Business School, Manchester, UK.
Anne MacFarlaneWHO Collaborating Centre for Participatory Health Research With Refugees and Migrants, School of Medicine, University of Limerick, Limerick, Ireland.
Frances S MairGeneral Practice & Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Sebastian PotthoffDepartment of Social Work, Education and Community Wellbeing, Northumbria University, Coach Lane Campus, Newcastle-Upon-Tyne, UK.
Tim RapleyDepartment of Social Work, Education and Community Wellbeing, Northumbria University, Coach Lane Campus, Newcastle-Upon-Tyne, UK.
Tracy L FinchDepartment of Nursing, Midwifery & Health, Northumbria University, Coach Lane Campus, Newcastle-Upon-Tyne, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImplementation strategies are deliberate systematic actions used to support the uptake of innovations in health and social care. While widely used taxonomies such as ERIC and EPOC have emerged from consensus exercises, few implementation strategies are explicitly derived from theory and tested against empirical data. This study develops a taxonomy of implementation strategies grounded in Normalization Process Theory (NPT), an implementation theory that explains how new practices become embedded and sustained.

methodsWe conducted a qualitative evidence synthesis of studies that reported implementation projects informed by NPT. Studies were identified through citation tracking and database searches, screened using pre-specified criteria, and appraised for methodological quality. Using the NPT coding manual, we identified implementation mechanisms described in each study and translated these into candidate implementation strategies. These were then tested against all included studies through iterative qualitative content analysis.

resultSearches led to 9,147 references, and we then eliminated 5,708 duplicates. After title and abstract screening a further 1,443 were eliminated. Full text screening was undertaken with 1,996 papers, and 1,411 of these were eliminated. This left 585 papers subjected to quality assessment, of which 522 were eliminated. Finally, 63 papers were included in the review. Qualitative analysis of included papers yielded 24 general strategies linked to NPT's theoretical constructs and 96 micro-strategies representing four domains of implementation activity: leadership, information, empowerment, and service user involvement. Each strategy was explicitly linked to an NPT construct.

conclusionsThis study provides a theory-based and empirically grounded set of actionable implementation strategies. These are grounded in qualitative descriptions of implementation work. These strategies support practical decision-making across the planning, delivery, and sustainment phases of implementation, and offer context-sensitive guidance for adapting interventions to diverse settings. Unlike consensus-based taxonomies, these strategies are tied to observable mechanisms of action, enabling users to better understand and respond to the dynamic and socially organised nature of implementation. The NPT taxonomy of implementation strategies can support the design, tailoring, and operationalisation of implementation efforts across varied health and social care contexts.

Indexed as

Implementation ScienceTranslational Research, BiomedicalDiffusion of InnovationHumansQualitative Research

Identifiers

PMID40717109
PMCPMC12297445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.