SynthesisInternational journal of geriatric psychiatry2025
Time to Diagnosis in Dementia: A Systematic Review With Meta-Analysis.
Synthesis in International journal of geriatric psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Time to Diagnosis in Dementia: A Systematic Review With Meta-Analysis.International journal of geriatric psychiatry · 2025Pooled it
- The value of timely treatment with anti-amyloid therapy for Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Primary care determinants for timely diagnosis of dementia.Family medicine and community health · 2026Article
- ["No shows" in dementia diagnostics: qualitative perspectives of patients and caregivers after a positive case finding by general practitioners].Zeitschrift fur Gerontologie und Geriatrie · 2026Article
- Coping Styles Predict Timing of Dementia Diagnosis: Evidence From DETERMIND.International journal of geriatric psychiatry · 2026Article
- Antidepressant use at the threshold: people prescribed antidepressants around the time of a dementia diagnosis.Age and ageing · 2026Article
- The Relationship Between Voluntary Rapid Blinking Rate and Future Development of Neurodegenerative Disease.Geriatrics & gerontology international · 2026Article
- The prevalence and incidence of young onset dementia in the Netherlands: a prospective study in two catchment areas.Alzheimer's research & therapy · 2026Article
- AI-driven predictive modeling of sarcopenia progression in limbic-predominant age-related TDP-43 encephalopathy: a novel biomarker fusion approach.Annals of medicine and surgery (2012) · 2026Article
- Bridging the diagnostic gap: Expanding dementia care navigation for timely diagnosis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Undiagnosed dementia and mortality among older adults in the United States and Brazil: A cross-national cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Disparities in the Setting of Initial Dementia Diagnosis: Influence of Race, Ethnicity, and Primary Care Use.Journal of the American Medical Directors Association · 2026Article
- The Impact of Dementia Caregiving on the Health of the Spousal Caregiver.Medicina (Kaunas, Lithuania) · 2026Review
- Development of a Prediction Model for Community-Dwelling Older Adults at Risk of Long-Term Care with Dementia.Geriatrics (Basel, Switzerland) · 2026Article
- Scientific knowledge about dementia: From the Global South to the world.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Review
- Co-designing a structured referral template to enhance dementia diagnosis: a modified e-Delphi study.Age and ageing · 2026Article
- Lithium therapy and delayed progression of Alzheimer's disease and related dementias in patients with bipolar disorder and mild neurocognitive disorders.medRxiv : the preprint server for health sciences · 2026Article
- Semi-Supervised Clustering for Identification of MCI and Dementia Cohorts with a Brief Digital Cognitive Assessment.Research square · 2026Article
- Prescribing trends and time series analysis of blood pressure-lowering drugs among patients with dementia: a multinational database study.EClinicalMedicine · 2025Article
- Editorial: Real-World Outcomes of Disease-Modifying Therapies Highlight the Need for Diagnostic Biomarkers in Early Alzheimer's Disease.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Timely dementia diagnosis is a global priority, reflected in most national and regional policies and plans. Nevertheless, there are currently no robust estimates of the average time to diagnosis (TTD) and factors influencing diagnostic intervals. This article presents the first systematic review of quantitative studies on TTD in dementia and the factors associated with its duration. We systematically searched EMBASE, Psych INFO, MEDLINE, and CINAHL databases for relevant studies published up to December 2024. We defined TTD as the interval between symptom onset (rated by family carers or patients using interviews or medical records) to final diagnosis. Risk of bias was assessed using the Reporting studies on time to diagnosis tool. We included 13 studies reporting data on 30,257 participants, with age at onset ranging between 54 and 93 years. Meta-analysis pooling 10 studies showed that average mean TTD across all types of dementia was 3.5 years [confidence interval (CI): 2.7-4.3; moderate quality evidence]. Analyses of six studies showed that TTD in young onset dementia was 4.1 years (CI: 3.4-4.9; moderate quality evidence). Although the factors influencing TTD were inconsistent, a younger age at onset and having frontotemporal dementia were consistently associated with a longer interval to diagnosis. TTD in dementia remains long, and specific healthcare strategies are urgently needed to improve it. Increasing the evidence base and developing interventions to reduce TTD should be a future research priority. Specialist services are likely to be key in improving TTD in young-onset dementia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.